Evidence map›Paper›PMID 23095870›Full record

ReviewHuman vaccines & immunotherapeutics2012

Allergen immunotherapy for allergic respiratory diseases.

Antonio Cappella, Stephen R Durham

Open access · bronzeAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Virus-like particle vaccinology, from bench to bedside.Cellular & molecular immunology · 2022
    Review
  4. Article
  5. Article
  6. Subcutaneous immunotherapy induces alterations in monocytes and dendritic cells homeostasis in allergic rhinitis patients.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018
    Article
  7. Review
  8. Article
  9. Article
  10. Alterations on peripheral blood B cell subsets induced by allergic rhinitis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2015
    Article
  11. Impact of allergic rhinitis and specific subcutaneous immunotherapy on peripheral blood basophils of patients sensitized to Dermatophagoides pteronyssinus.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2013
    Article
  12. Recent changes in the drug treatment of allergic asthma.Clinical medicine (London, England) · 2013
    Review
  13. Review
  14. [Allergic immunotherapy in children and adolescents].Revue francaise d'allergologie (2009)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Antonio CappellaSection Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College, London, UK.
Stephen R Durham
Imperial Valley College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen specific immunotherapy involves the repeated administration of allergen products in order to induce clinical and immunologic tolerance to the offending allergen. Immunotherapy is the only etiology-based treatment that has the potential for disease modification, as reflected by longterm remission following its discontinuation and possibly prevention of disease progression and onset of new allergic sensitizations. Whereas subcutaneous immunotherapy is of proven value in allergic rhinitis and asthma there is a risk of untoward side effects including rarely anaphylaxis. Recently the sublingual route has emerged as an effective and safer alternative. Whereas the efficacy of SLIT in seasonal allergy is now well-documented in adults and children, the available data for perennial allergies and asthma is less reliable and particularly lacking in children. This review evaluates the efficacy, safety and longterm benefits of SCIT and SLIT and highlights new findings regarding mechanisms, potential biomarkers and recent novel approaches for allergen immunotherapy.

Indexed as

Adjuvants, ImmunologicAnimalsDesensitization, ImmunologicHumansHypersensitivityRespiratory HypersensitivityAdjuvants, Immunologicadjuvantallergen vaccineimmunopotentiatorsublingual immunotherapyvector system

Identifiers

PMID23095870
PMCPMC3660772
OpenAlexW1975748931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.