Evidence map›Paper›PMID 23095400›Full record

ArticleThe Behavioral and brain sciences2012

Parental brain and socioeconomic epigenetic effects in human development.

James E Swain, Suzanne C Perkins, Carolyn J Dayton, Eric D Finegood, S Shaun Ho

Abstract readComment
In one paragraph

Article in The Behavioral and brain sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

James E SwainDepartment of Psychiatry, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA. jamesswa@med.umich.edu
Suzanne C Perkins
Carolyn J Dayton
Eric D Finegood
S Shaun Ho

Funding

MICHIGAN INSTITUTE FOR CLINICAL AND HEALTH RESEARCH (MICHR) (UL1): (BPCA)UL1RR024986 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2007 to 2011
$51.2M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Childhood Poverty and Brain Development: The Role of Chronic Stress and ParentingRC2MD004767 · NIMHD · CORNELL UNIVERSITY · PI EVANS, GARY W, LIBERZON, ISRAEL · 2009 to 2010
$1.4M
NCATS NIH HHS UL1 TR000433NCRR NIH HHS UL1 RR024986NCRR NIH HHS UL1RR024986NIMHD NIH HHS NIMHD IRC2MD004767-01NIMHD NIH HHS RC2 MD004767
6 · The paper itself

Abstract

Critically significant parental effects in behavioral genetics may be partly understood as a consequence of maternal brain structure and function of caregiving systems recently studied in humans as well as rodents. Key parental brain areas regulate emotions, motivation/reward, and decision making, as well as more complex social-cognitive circuits. Additional key environmental factors must include socioeconomic status and paternal brain physiology. These have implications for developmental and evolutionary biology as well as public policy.

Indexed as

Genetics, BehavioralGenomicsFemaleHumansPregnancy

Identifiers

PMID23095400
PMCPMC4317260

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.