ArticleThe Behavioral and brain sciences2012
Non-Mendelian etiologic factors in neuropsychiatric illness: pleiotropy, epigenetics, and convergence.
Article in The Behavioral and brain sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Synthetic threads through the web of life.Proceedings of the National Academy of Sciences of the United States of America · 2021Review
- Is There a Characteristic Autonomic Response During Outbursts of Combative Behavior in Dementia Patients?Journal of Alzheimer's disease reports · 2021Article
- Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification.Clinical epigenetics · 2020Review
- Repository of Human Blood Derivative Biospecimens in Biobank: Technical Implications.Middle East journal of digestive diseases · 2015Review
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Authors and funding
2 authors.
Funding
Abstract
The target article by Charney on behavior genetics/genomics discusses how numerous molecular factors can inform heritability estimations and genetic association studies. These factors find application in the search for genes for behavioral phenotypes, including neuropsychiatric disorders. We elaborate upon how single causal factors can generate multiple phenotypes, and discuss how multiple causal factors may converge on common neurodevelopmental mechanisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.