ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2013
Mitral annular calcification is associated with pulse wave velocity but not with augmentation index.
Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Assessment of Arterial Stiffness with Cardio-Ankle Vascular Index in Patients with Mitral Annular Calcification.The Eurasian journal of medicine · 2021Article
- The Forgotten Variable of Shear Stress in Mitral Annular Calcification: Whole Blood Viscosity.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2015Article
- Arterial stiffness may be associated with mitral annular calcification based on inflammatory condition.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2014Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the possible relationship between mitral annular calcification (MAC) and arterial stiffness. SUBJECTS AND
methodsForty-two patients (mean age 68 ± 6 years) with MAC and an age-matched control group of 41 individuals (mean age 66 ± 6 years) were studied. Arterial stiffness and wave reflections of the study population were evaluated by using applanation tonometry (SphygmoCor). Aortic pulse wave velocity (PWV) was measured as an index of aortic stiffness. The heart rate-corrected augmentation index (AIx@75) was estimated as a composite marker of wave reflections and arterial stiffness.
resultsAortic PWV was significantly higher in patients with MAC (12.2 ± 2.3 m/s) than in controls (10.1 ± 1.3 m/s, p = 0.0001). However, AIx@75 was similar between the groups (28 ± 10 vs. 29 ± 10%, p = 0.59). Multivariate analysis involving the whole population revealed that brachial diastolic blood pressure (β = 1.87, p = 0.04) and MAC (β = 0.41, p = 0.0001) were independent determinants of aortic PWV.
conclusionThe data showed that MAC was significantly associated with increased arterial stiffness and that it was an independent determinant of aortic PWV.
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