Evidence map›Paper›PMID 23094178›Full record

ArticleCase reports in psychiatry2012

Agomelatine augmentation of escitalopram therapy in treatment-resistant obsessive-compulsive disorder: a case report.

Domenico De Berardis, Nicola Serroni, Stefano Marini, Giovanni Martinotti, Francesca Ferri, Gaetano Callista, Raffaella La Rovere, Francesco Saverio Moschetta, Massimo Di Giannantonio

Open access · goldAbstract read
In one paragraph

Article in Case reports in psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. OCDB: a database collecting genes, miRNAs and drugs for obsessive-compulsive disorder.Database : the journal of biological databases and curation · 2015
    Article
  4. Microstructural abnormality in left nucleus accumbens predicts dysfunctional beliefs in treatment-resistant obsessive-compulsive disorder.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Article
  5. Article
  6. Agomelatine-induced hepatotoxicity.Wiener klinische Wochenschrift · 2013
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Domenico De BerardisNHS, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital "G. Mazzini", ASL 4, 64100 Teramo, Italy ; Department of Neurosciences and Imaging, Chair of Psychiatry, University "G. D'Annunzio", 66100 Chieti, Italy.
Nicola Serroni
Stefano Marini
Giovanni Martinotti
Francesca Ferri
Gaetano Callista
Raffaella La Rovere
Francesco Saverio Moschetta
Massimo Di Giannantonio
University of Chieti-Pescara · ITSanta Maria Nuova Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obsessive-compulsive disorder (OCD) is a chronic condition characterized by obsessions or compulsions that cause distress or interfere with functioning. Selective serotonin reuptake inhibitors are the first-line strategy in the treatment of OCD, but approximately 40% to 60% of patients with OCD fail to respond to them. Several augmentation strategies have been proposed, including the use of atypical antipsychotics and antidepressant combinations. In the present paper we describe the case of a young female patient suffering from severe treatment-resistant OCD who remitted as a result of agomelatine augmentation of escitalopram therapy.

Identifiers

PMID23094178
PMCPMC3474211
OpenAlexW2116736512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.