ArticleJournal of biomedicine & biotechnology2012
Simulating radiotherapy effect in high-grade glioma by using diffusive modeling and brain atlases.
Article in Journal of biomedicine & biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Mechanistic mathematical modeling of abscopal effect reveals mechanisms of off-target tumor response.Frontiers in immunology · 2026Article
- The impact of tumor microenvironment and treatment schedule on the effectiveness of radiation therapy.PloS one · 2025Article
- Article
- In Silico Mathematical Modelling for Glioblastoma: A Critical Review and a Patient-Specific Case.Journal of clinical medicine · 2021Review
- Evolution of Human Brain Atlases in Terms of Content, Applications, Functionality, and Availability.Neuroinformatics · 2021Review
- Corrigendum to "Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases".BioMed research international · 2018Article
- Clinical implications of in silico mathematical modeling for glioblastoma: a critical review.Journal of neuro-oncology · 2018Review
- Post-Surgery Glioma Growth Modeling from Magnetic Resonance Images for Patients with Treatment.Scientific reports · 2017Article
- Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma.Journal of therapeutic ultrasound · 2016Article
- A Proposed Paradigm Shift in Initializing Cancer Predictive Models with DCE-MRI Based PK Parameters: A Feasibility Study.Cancer informatics · 2015Article
- Comment on "Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases".BioMed research international · 2015Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Applying diffusive models for simulating the spatiotemporal change of concentration of tumour cells is a modern application of predictive oncology. Diffusive models are used for modelling glioblastoma, the most aggressive type of glioma. This paper presents the results of applying a linear quadratic model for simulating the effects of radiotherapy on an advanced diffusive glioma model. This diffusive model takes into consideration the heterogeneous velocity of glioma in gray and white matter and the anisotropic migration of tumor cells, which is facilitated along white fibers. This work uses normal brain atlases for extracting the proportions of white and gray matter and the diffusion tensors used for anisotropy. The paper also presents the results of applying this glioma model on real clinical datasets.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.