ArticleEmerging infectious diseases2012
Unchanged severity of influenza A(H1N1)pdm09 infection in children during first postpandemic season.
Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Characteristics and outcome of ill critical patients with influenza A infection.The Pan African medical journal · 2018Article
- Performance of a Taqman Assay for Improved Detection and Quantification of Human Rhinovirus Viral Load.Scientific reports · 2016Article
- Continued high incidence of children with severe influenza A(H1N1)pdm09 admitted to paediatric intensive care units in Germany during the first three post-pandemic influenza seasons, 2010/11-2012/13.BMC infectious diseases · 2015Article
- Effectiveness of non-pharmaceutical measures in preventing pediatric influenza: a case-control study.BMC public health · 2015Article
- Influenza in hospitalized children in Ireland in the pandemic period and the 2010/2011 season: risk factors for paediatric intensive-care-unit admission.Epidemiology and infection · 2014Article
- Epidemiology of influenza virus types and subtypes in South Africa, 2009-2012.Emerging infectious diseases · 2014Article
- Differential use of antivirals for treatment of patients with influenza A(H1N1)pdm09 in Germany.Influenza and other respiratory viruses · 2013Article
- Changes in severity of influenza A(H1N1)pdm09 infection from pandemic to first postpandemic season, Germany.Emerging infectious diseases · 2013Article
- Article
- Viral detection profile in children with severe acute respiratory infection.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesObservational
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Authors and funding
6 authors.
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Abstract
We conducted a nationwide hospital-based prospective study in Germany of influenza A(H1N1)pdm09 cases among children <15 years of age admitted to pediatric intensive care units and related deaths during the 2009-10 pandemic and the 2010-11 postpandemic influenza seasons. We identified 156 eligible patients: 112 in 2009-10 and 44 in 2010-11. Although a shift to younger patients occurred in 2010-11 (median age 3.2 vs. 5.3 years), infants <1 year of age remained the most affected. Underlying immunosuppression was a risk factor for hospital-acquired infections (p = 0.013), which accounted for 14% of cases. Myocarditis was predictive of death (p = 0.006). Of the 156 case-patients, 17% died; the difference between seasons was not significant (p = 0.473). Our findings stress the challenge of preventing severe postpandemic influenza infection in children and the need to prevent nosocomial transmission of influenza virus, especially in immunosuppressed children.
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