ArticleThe American journal of tropical medicine and hygiene2012
Brucellosis among hospitalized febrile patients in northern Tanzania.
Article in The American journal of tropical medicine and hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Systematic review of brucellosis in Kenya: disease frequency in humans and animals and risk factors for human infection.BMC public health · 2016Pooled it
- Prevalence and speciation of brucellosis in febrile patients from a pastoralist community of Tanzania.Scientific reports · 2020Trial
- Seroprevalence and risk factors for Brucella species and Coxiella burnetii exposure in a cross-sectional serosurvey of occupationally exposed groups in peri-urban Lomé, Togo.PLoS neglected tropical diseases · 2026Article
- Knowledge, Attitude and Practices Regarding Tick-Borne Diseases Among Healthcare Workers in Two Hospitals in Kilimanjaro, Tanzania: A Cross-Sectional Study.Journal of parasitology research · 2026Article
- Malaria misdiagnosis substantially contributes to the underestimation of global human brucellosis incidence.BMC public health · 2025Article
- TaqMan Array Card real-time polymerase chain reaction panel to detect pathogens in whole blood of febrile inpatients in northern Tanzania, 2016-2019.Tropical medicine & international health : TM & IH · 2025Article
- Article
- Pillars for successful operationalization of one health as an ecosystem approach: experience from a human-animal interface in the Maasai steppe in Tanzania.One health outlook · 2023Article
- The effects of health education intervention on promoting knowledge, beliefs and preventive behaviors on brucellosis among rural population in Nagpur district of Maharashtra state, India.Journal of family medicine and primary care · 2022Article
- Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania.Scientific reports · 2022Article
- Knowledge, attitude and practices of frontline health workers in relation to detection of brucellosis in rural settings of Tanzania: a cross-sectional study.One health outlook · 2022Article
- Brucellosis testing patterns at health facilities in Arusha region, northern Tanzania.PloS one · 2022Article
- Knowledge of Brucellosis, Health-Seeking Behaviour, and Risk Factors forPathogens (Basel, Switzerland) · 2021Article
- Prevalence and risk factors of human brucellosis and malaria among patients with fever in malaria-endemic areas, attending health institutes in Awra and Gulina district, Afar Region, Ethiopia.BMC infectious diseases · 2021Article
- Lay attitudes and misconceptions and their implications for the control of brucellosis in an agro-pastoral community in Kilombero district, Tanzania.PLoS neglected tropical diseases · 2021Article
- Brucellosis: Prevalence with reference to East African community countries - A rapid review.Veterinary medicine and science · 2021Review
- Performance characteristics and costs of serological tests for brucellosis in a pastoralist community of northern Tanzania.Scientific reports · 2021Article
- Rickettsial Infections among the Undifferentiated Febrile Patients Attending a Tertiary Care Teaching Hospital of Northern India: A Longitudinal Study.Infection & chemotherapy · 2021Article
- Factors Associated with Delayed Diagnosis of Cervical Cancer in Tikur Anbesa Specialized Hospital, Ethiopia, 2019: Cross-Sectional Study.Cancer management and research · 2021Article
- Sensitivity of C-reactive protein for the identification of patients with laboratory-confirmed bacterial infections in northern Tanzania.Tropical medicine & international health : TM & IH · 2020Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
Acute and convalescent serum samples were collected from febrile inpatients identified at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive blood culture or a ≥ 4-fold increase in microagglutination test titer, and probable brucellosis was defined as a single reciprocal titer ≥ 160. Among 870 participants enrolled in the study, 455 (52.3%) had paired sera available. Of these, 16 (3.5%) met criteria for confirmed brucellosis. Of 830 participants with ≥ 1 serum sample, 4 (0.5%) met criteria for probable brucellosis. Brucellosis was associated with increased median age (P = 0.024), leukopenia (odds ratio [OR] 7.8, P = 0.005), thrombocytopenia (OR 3.9, P = 0.018), and evidence of other zoonoses (OR 3.2, P = 0.026). Brucellosis was never diagnosed clinically, and although all participants with brucellosis received antibacterials or antimalarials in the hospital, no participant received standard brucellosis treatment. Brucellosis is an underdiagnosed and untreated cause of febrile disease among hospitalized adult and pediatric patients in northern Tanzania.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.