Trial reportMolecular imaging and biology2013
Dynamic changes of FDG uptake and clearance in normal tissues.
Trial report in Molecular imaging and biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 98 citations in OpenAlex.
- Quantification of FDG-PET/CT with delayed imaging in patients with newly diagnosed recurrent breast cancer.BMC medical imaging · 2018Trial
- Cardiovascular implantable electronic device infection: delayed vs standard FDG PET-CT imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Trial
- Enhanced Uptake of FDG in PET/CT After the Use of Bone Wax During Sternotomy.The Thoracic and cardiovascular surgeon · 2026Article
- Modelling image quality over extended [Frontiers in oncology · 2026Article
- A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2025Article
- Diagnostic accuracy of dual-phaseScientific reports · 2025Article
- Analysis of the best time-point for 18F-FDG PET/CT delayed imaging in patients of small colorectal cancer liver metastasis with hypothyroidism based on diagnostic efficacy and image standardized uptake values.Annals of nuclear medicine · 2025Article
- Distinct bone metabolic networks identified inFrontiers in medicine · 2025Article
- Optimisation of Animal Handing and Timing of 2-deoxy-2-[Molecular imaging and biology · 2024Article
- Total-body dynamic PET/CT imaging reveals kinetic distribution of [European journal of nuclear medicine and molecular imaging · 2024Article
- The role of dynamic, static, and delayed total-body PET imaging in the detection and differential diagnosis of oncological lesions.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- The feasibility of quantitative assessment of dynamicEuropean journal of nuclear medicine and molecular imaging · 2023Article
- Prone position PET/CT is useful in reducing gravity-dependent opacity-related [European radiology · 2023Article
- Review
- The Spectrum of Solitary Benign Splenic Lesions-Imaging Clues for a Noninvasive Diagnosis.Diagnostics (Basel, Switzerland) · 2023Review
- Investigation of tumor assessment between two PET systems using various indices: comparison between PET/CT and PET/MRI systems.American journal of nuclear medicine and molecular imaging · 2023Article
- Dual time point imaging in locally advanced head and neck cancer to assess residual nodal disease after chemoradiotherapy.EJNMMI research · 2022Article
- What's in a node? The clinical and radiologic significance of Virchow's node.Abdominal radiology (New York) · 2022Review
- Advantages and Applications of Total-Body PET Scanning.Diagnostics (Basel, Switzerland) · 2022Review
- Kinetic metrics ofEuropean journal of nuclear medicine and molecular imaging · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims to evaluate dynamic 2-deoxy-2-[(18)F]fluoro-D-glucose (FDG) uptake in normal tissues. PROCEDURES: Thirty male patients underwent FDG positron emission tomography (PET)/computed tomography imaging at 1, 2, and 3 h after tracer injection. Standardized uptake values (SUV) were obtained in regions of interest of normal tissues.
resultsThe aorta (blood pool), liver, and spleen FDG activity demonstrated significantly and continuously decreased activity from 1 to 2 and 2 to 3 h, while FDG uptake in the lungs, pancreas, lymph nodes, and skeletal muscle decreased from 1 to 2 h only. In contrast, the left ventricular myocardium demonstrated two patterns of dynamic changes: myocardium with higher FDG uptake (SUVmax ≥ 3.25) on the initial images had more remarkable increased activity on the delayed images, while myocardium with lower FDG uptake (SUVmax < 3.25) on the initial imaging had no increased uptake on delayed imaging. Increased FDG uptake was also observed in the bones on the delayed images. No significant changes of FDG uptake were noted in the parotid gland, thyroid gland, and prostate gland.
conclusionsThese findings may help nuclear medicine physicians when comparing images performed at different time points, when using FDG uptake in internal reference regions as a relative indicator of FDG uptake in a specific lesion, and when reading a delayed FDG PET imaging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.