Evidence map›Paper›PMID 23090462›Full record

ArticleClinical obstetrics and gynecology2012

Neonatal herpes simplex virus infection.

Thomas L Cherpes, Dean B Matthews, Samantha A Maryak

Abstract read
In one paragraph

Article in Clinical obstetrics and gynecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. CD71Scientific reports · 2017
    Article
  8. Article
  9. Article
  10. P-TEFb goes viral.Inside the cell · 2016
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thomas L CherpesDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. cherpestl@upmc.edu
Dean B Matthews
Samantha A Maryak
University of Pittsburgh · US

Funding

Modulation of Hormonal and Systemic Immunity by Hormonal Contraceptive UseR01HD072663 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TROUT, WAYNE C · 2012 to 2016
$2.1M
Tregs:sculpting a balance between protection and pathology during viral infectionR56AI085110 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHERPES, THOMAS L. · 2010 to 2010
$374k
NIAID NIH HHS R56 AI085110NIAID NIH HHS R56AI85110NICHD NIH HHS R01 HD072663
6 · The paper itself

Abstract

Neonatal herpes, seen roughly in 1 of 3000 live births in the United States, is the most serious manifestation of herpes simplex virus (HSV) infection in the perinatal period. Although acyclovir therapy decreases infant mortality associated with perinatal HSV transmission, development of permanent neurological disabilities is not uncommon. Mother-to-neonate HSV transmission is most efficient when maternal genital tract HSV infection is acquired proximate to the time of delivery, signifying that neonatal herpes prevention strategies need to focus on decreasing the incidence of maternal infection during pregnancy and more precisely identifying infants most likely to benefit from prophylactic antiviral therapy.

Indexed as

Herpesvirus 1, HumanHerpesvirus 2, HumanAntibodies, ViralCentral Nervous System DiseasesFemaleHerpes GenitalisHerpes SimplexHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousUnited StatesAntibodies, Viral

Identifiers

PMID23090462
PMCPMC3479667
OpenAlexW2042998390

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.