ArticlePediatric surgery international2012
Trends in the treatment and outcome of congenital diaphragmatic hernia over the last decade.
Article in Pediatric surgery international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study.Annals of epidemiology · 2021Article
- Congenital diaphragmatic hernia presenting with symptoms within the first day of life; outcomes from a non-ECMO centre in Denmark.BMC pediatrics · 2020Article
- Anesthetic management of a neonate with congenital diaphragmatic hernia under high-frequency oscillatory ventilation.Clinics and practice · 2018Article
- Intestinal Perforation during the Stabilization Period in a Preterm Infant with Congenital Diaphragmatic Hernia.European journal of pediatric surgery reports · 2017Article
- Congenital diaphragmatic hernia, management in the newborn.Pediatric surgery international · 2015Review
- Outcome of right-sided diaphragmatic hernia repair: a multicentre study.Pediatric surgery international · 2015Article
- Extracorporeal life support in patients with congenital diaphragmatic hernia: how long should we treat?Journal of the American College of Surgeons · 2014Article
- Disruption of THY-1 signaling in alveolar lipofibroblasts in experimentally induced congenital diaphragmatic hernia.Pediatric surgery international · 2014Article
- Cord blood endothelial colony-forming cells from newborns with congenital diaphragmatic hernia.The Journal of pediatrics · 2013Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCongenital diaphragmatic hernia (CDH) remains a challenging and life-threatening congenital anomaly. The aim was to evaluate whether treatment and survival has changed during the last decade.
methodsWe retrospectively analysed all consecutive infants with CDH referred to two European tertiary paediatric surgical centres over 11 years (January 1999 to December 2009). Minimum follow-up was 1 year. χ(2) test for trend was used to evaluate significance.
resultsThere were 234 infants. There was no significant variation over time in the proportion of infants receiving high frequency oscillatory ventilation (HFOV) (p = 0.89), inhaled nitric oxide (iNO) (p = 0.90) or extracorporeal membrane oxygenation (ECMO) (p = 0.22). 205 infants (88 %) were stabilised and underwent surgical repair; of these, 186 (79 %) survived after surgery. Over time there was a significant increase in the proportion of infants undergoing surgical repair (p = 0.018) without a concomitant significant improvement in survival (p = 0.099).
conclusionThis multicentre analysis indicates that the survival rate of infants with CDH referred to two European paediatric surgical centres is high (79 %). The use of HFOV, iNO and ECMO has not changed in recent years. We observed a significant increase in the proportion of infants who undergo surgery but this has not resulted in a significant increase in the overall survival rate.
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