Evidence map›Paper›PMID 23089927›Full record

ReviewExercise and sport sciences reviews2013

Measuring protein synthesis with SUnSET: a valid alternative to traditional techniques?

Craig A Goodman, Troy A Hornberger

Abstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

156 citing papers in PubMed.

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  16. GL261 glioblastoma induces delayed body weight gain and stunted skeletal muscle growth in young mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
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96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Craig A GoodmanDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA. cgoodman2@wisc.edu
Troy A Hornberger

Funding

Mechanotransduction and the Regulation of Skeletal Muscle MassR01AR057347 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI HORNBERGER, TROY A · 2010 to 2019
$3.6M
Mechanotransduction and the Regulation of Skeletal Muscle MassR56AR057347 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI HORNBERGER, TROY A · 2022 to 2022
$270k
NIAMS NIH HHS AR057347NIAMS NIH HHS R01 AR057347NIAMS NIH HHS R56 AR057347
6 · The paper itself

Abstract

Protein synthesis rates commonly are measured using isotopic tracers to quantify the incorporation of a labeled amino acid into muscle proteins. Here we provide evidence supporting our hypothesis that the nonisotopic SUnSET technique is a valid and accurate method for the measurement of in vivo changes in protein synthesis at the whole-muscle and single-muscle fiber levels.

Indexed as

Protein Synthesis InhibitorsPuromycinAnimalsHumansMuscle ProteinsMuscle, SkeletalMuscle ProteinsProtein Synthesis InhibitorsPuromycin

Identifiers

PMID23089927
PMCPMC3951011

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.