ArticleNature chemistry2012
Prebiotic synthesis of simple sugars by photoredox systems chemistry.
Article in Nature chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
What it found
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Who cites it
94 citing papers in PubMed, 252 citations in OpenAlex.
- Prebiotically Plausible Synthesis of N-Cyanoimidazole for Phosphate Activation and Templated RNA Ligation.Journal of the American Chemical Society · 2026Article
- Article
- Shadow of a Shadow: Ferrocyanide and Nitroprusside as Sunscreens for Photosensitive Prebiotic Molecules.Life (Basel, Switzerland) · 2026Article
- Redox chemistry of early Earth and the origin of life.Communications chemistry · 2026Review
- Molecular Dissipative Structuring: The Fundamental Creative Force in Biology.Entropy (Basel, Switzerland) · 2026Review
- Complex and Messy Prebiotic Chemistry: Obstacles and Opportunities for an RNA World.Life (Basel, Switzerland) · 2026Review
- Revisiting the Glucose Kinase Superfamily: From Origins to the Evolution of Metabolism.Genome biology and evolution · 2025Article
- Magmatic immiscibility provides phosphate for prebiotic chemistry.Science advances · 2025Article
- Autocatalytic Reaction between HCN and Cysteamine Produces Hydrophobic, Catalytic, Liquid Compartments.Journal of the American Chemical Society · 2025Article
- Intercepting Methanimine for the Synthesis of Piperidine-BasedThe Journal of organic chemistry · 2025Article
- Phosphorylation of nucleosides by P-N bond species generated from prebiotic reduced phosphorus sources.Communications chemistry · 2025Article
- Origin of the RNA World in Cold Hadean Geothermal Fields Enriched in Zinc and Potassium: Abiogenesis as a Positive Fallout from the Moon-Forming Impact?Life (Basel, Switzerland) · 2025Article
- Probing the Limits of Reactant Concentration and Volume in Primitive Polyphenyllactate Synthesis and Microdroplet Assembly Processes.ACS bio & med chem Au · 2025Article
- Article
- Groundwater-Driven Evolution of Prebiotic Alkaline Lake Environments.Life (Basel, Switzerland) · 2024Article
- Iron sulfide-catalyzed gaseous CONature communications · 2024Article
- Mimicking lightning-induced electrochemistry on the early Earth.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Prebiotic thiol-catalyzed thioamide bond formation.Geochemical transactions · 2024Article
- The Pigment World: Life's Origins as Photon-Dissipating Pigments.Life (Basel, Switzerland) · 2024Article
- Light-Assisted Formation of Nucleosides and Nucleotides from Formamide in the Presence of Cerium Phosphate.Life (Basel, Switzerland) · 2024Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A recent synthesis of activated pyrimidine ribonucleotides under prebiotically plausible conditions relied on mixed oxygenous and nitrogenous systems chemistry. As it stands, this synthesis provides support for the involvement of RNA in the origin of life, but such support would be considerably strengthened if the sugar building blocks for the synthesis--glycolaldehyde and glyceraldehyde--could be shown to derive from one carbon feedstock molecules using similarly mixed oxygenous and nitrogenous systems chemistry. Here, we show that these sugars can be formed from hydrogen cyanide by ultraviolet irradiation in the presence of cyanometallates in a remarkable systems chemistry process. Using copper cyanide complexes, the process operates catalytically to disproportionate hydrogen cyanide, first generating the sugars and then sequestering them as simple derivatives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.