Trial reportJournal of consulting and clinical psychology2012
Comparative effectiveness of medication versus cognitive-behavioral therapy in a randomized controlled trial of low-income young minority women with depression.
Trial report in Journal of consulting and clinical psychology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents.The Cochrane database of systematic reviews · 2014Pooled it
- Trial
- Preliminary Effects of Mindfulness Training on Inflammatory Markers and Blood Pressure in Young Adult Survivors of Cancer: Secondary Analysis of a Pilot Randomized Controlled Trial.International journal of behavioral medicine · 2022Trial
- A Randomized Comparison of Medication and Cognitive Behavioral Therapy for Treating Depression in Low-Income Young Minority Women.Medical science monitor : international medical journal of experimental and clinical research · 2016Trial
- Predictors of prevention failure in college students participating in two indicated depression prevention programs.International journal of environmental research and public health · 2014Trial
- Blood Pressure Trajectories During Young Adulthood and Cardiovascular Events in Later Life.American journal of hypertension · 2024Article
- Primary Care Clinic Approaches to Facilitating Patient Health Behavior Change in Alabama.Cureus · 2024Article
- Three Flavorings for a Soup to Cure what Ails Mental Health Services.Administration and policy in mental health · 2020Article
- Fasting glucose and insulin resistance trajectories during young adulthood and mid-life cardiac structure and function.Journal of diabetes and its complications · 2019Observational
- Testing moderation in network meta-analysis with individual participant data.Statistics in medicine · 2016Article
- Disparities in antidepressant use in pregnancy.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
- Blood pressure trajectories in early adulthood and subclinical atherosclerosis in middle age.JAMA · 2014Article
- Practitioner review: maternal mood in pregnancy and child development--implications for child psychology and psychiatry.Journal of child psychology and psychiatry, and allied disciplines · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo examine whether there are latent trajectory classes in response to treatment and whether they moderate the effects of medication versus psychotherapy.
methodData come from a 1-year randomized controlled trial of 267 low-income, young (M = 29 years), minority (44% Black, 50% Latina, 6% White) women with current major depression randomized to antidepressants, cognitive-behavioral therapy (CBT), or referral to community mental health services. Growth mixture modeling was used to determine whether there were differential effects of medication versus CBT. Depression was measured via the Hamilton Depression Rating Scale (Hamilton, 1960).
resultsWe identified 2 latent trajectory classes. The first was characterized by severe depression at baseline. At 6 months, mean depression scores for the medication and CBT groups in this class were 13.9 and 14.9, respectively (difference not significant). At 12 months, mean depression scores were 16.4 and 11.0, respectively (p for difference = .04). The second class was characterized by moderate depression and anxiety at baseline. At 6 months, mean depression scores for the medication and CBT groups were 4.4 and 6.8, respectively (p for difference = .03). At 12 months, the mean depression scores were 7.1 and 7.8, respectively, and the difference was no longer significant.
conclusionsAmong depressed women with moderate baseline depression and anxiety, medication was superior to CBT at 6 months, but the difference was not sustained at 1 year. Among women with severe depression, there was no significant treatment group difference at 6 months, but CBT was superior to medication at 1 year.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.