ArticleSpermatogenesis2012
Development of sexual dimorphism in the Drosophila testis.
Article in Spermatogenesis, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
- Faster and smaller: Heterochronic shift in gene expression leads to larval onset of spermatogenesis and miniaturized males.iScience · 2026Article
- Sex-converted testis somatic cells acquire female-specific behaviors and alter XY germline identity.Development (Cambridge, England) · 2025Article
- Article
- Testis- and ovary-expressed polo-like kinase transcripts and gene duplications affect male fertility when expressed in the Drosophila melanogaster germline.G3 (Bethesda, Md.) · 2025Article
- Differential amino acid transporter expression in adultmicroPublication biology · 2024Article
- Different mechanisms of X-ray irradiation-induced male and female sterility in Aedes aegypti.BMC biology · 2023Article
- NInsect biochemistry and molecular biology · 2023Article
- Modest sexual size dimorphism and allometric growth: a study based on growth and gonad development in the wolf spider Pardosa pseudoannulata (Araneae: Lycosidae).Biology open · 2021Article
- The βScientific reports · 2021Article
- New data on spermatogenic cyst formation and cellular composition of the testis in a marine gastropod,International journal of molecular sciences · 2020Article
- Chinmo is sufficient to induce male fate in somatic cells of the adult Drosophila ovary.Development (Cambridge, England) · 2016Article
- The Jak-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche.Developmental cell · 2014Article
- Article
- Overview: Special issue on Drosophila spermatogenesis.Spermatogenesis · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The creation of sexual dimorphism in the gonads is essential for producing the male and female gametes required for sexual reproduction. Sexual development of the gonads involves both somatic cells and germ cells, which often undergo sex determination by different mechanisms. While many sex-specific characteristics evolve rapidly and are very different between animal species, gonad function and the formation of sperm and eggs appear more similar and may be more conserved. Consistent with this, the doublesex/mab3 Related Transcription factors (DMRTs) are important for gonad sexual dimorphism in a wide range of animals, including flies, worms and mammals. Here we explore how sexual dimorphism is regulated in the Drosophila gonad, focusing on recent discoveries relating to testis development. We will discuss how sex determination in both the germline and the soma are utilized to create a testis, including the role of the key somatic sex determination factor doublesex.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.