ArticleSurgical neurology international2012
Natural history of hydrocephalus in children with spinal open neural tube defect.
Article in Surgical neurology international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Endoscopic third ventriculostomy versus ventriculoperitoneal shunt in pediatric and adult population: a systematic review and meta-analysis.Neurosurgical review · 2021Pooled it
- Impact of surgical timing and concomitant anomalies on neonatal meningomyelocele outcomes: a single-center experience.Neurosurgical review · 2025Article
- Myelomeningocele: Long-Term Neurosurgical Management.Advances and technical standards in neurosurgery · 2024Review
- A neural stem cell paradigm of pediatric hydrocephalus.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Perspectives on urological care in spina bifida patients.Intractable & rare diseases research · 2021Review
- Article
- Not all ventriculomegaly is created equal: diagnostic overview of fetal, neonatal and pediatric ventriculomegaly.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report.BMC research notes · 2017Article
- First 60 fetal in-utero myelomeningocele repairs at Saint Louis Fetal Care Institute in the post-MOMS trial era: hydrocephalus treatment outcomes (endoscopic third ventriculostomy versus ventriculo-peritoneal shunt).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- The problem with myelomeningoceles, hydrocephalus, and progressive neurological deficits-what do we know?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- A comparison of the MOMS trial results to a contemporaneous, single-institution, postnatal closure cohort.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus.Fluids and barriers of the CNS · 2016Article
- Hydrocephalus in patients with closed neural tube defects.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Agenesis of the corpus callosum associated with spinal open neural tube defect.Saudi medical journal · 2014Article
- Classification, clinical features, and genetics of neural tube defects.Saudi medical journal · 2014Review
- Epidemiology, prenatal management, and prevention of neural tube defects.Saudi medical journal · 2014Review
- Concomitant achondroplasia and Chiari II malformation: A double-hit at the cervicomedullary junction.World journal of clinical cases · 2014Article
- Myelomeningocele: the management of the associated hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Review
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Authors and funding
1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe long-term prognosis of patients with Spinal Open Neural Tube Defect (SONTD)-associated hydrocephalus is not well known. This study was conducted to ascertain the incidence and natural history of hydrocephalus in patients with SONTD.
methodsAll 82 patients with SONTD referred to Neurosurgery/Spina Bifida Clinics at King Khalid University Hospital, Riyadh, Saudi Arabia (January 1995 - July 2010) were studied and followed for a period of 1-16 years. Patients were divided into three groups: Group "A" with active hydrocephalus treated with ventriculoperitoneal shunt (VPS), or endoscopic third ventriculostomy (ETV); Group "B" with compensated hydrocephalus; and Group "C" with no hydrocephalus. Timing of shunt insertion, complications of treatment and status of hydrocephalus were analyzed.
resultsThe mean age of the 82 patients was 7.4 years (range 1-16 years). Group "A" included 59 (72%) patients, Group "B" 7 (8.5%) patients, and Group "C" 16 (19.5%) patients. Chiari malformation type II was found in 71 (86.6%) patients, 57 of whom (80%) were in Group "A" with active hydrocephalus. They were treated by VPS (51 patients) and ETV (8 patients). The shunts were revised or replaced in 10 (19.6%) patients due to obstruction or infection. Primary ETV failed in 3/8 patients, and treated by VPS. None of those in Groups "B" or "C" required treatment for hydrocephalus during the follow up.
conclusionHydrocephalus affects the majority of patients with SONTD who have Myelomeningocele (MMC) and CM II and requires close surveillance and prompt management. Children with SONTD should routinely undergo MRI examination of brain and craniocervical junction to clarify ventricular size, and the presence of CM II.
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