Evidence map›Paper›PMID 23087512›Full record

ArticleIndian journal of pharmacology

Analgesic activity of the ethanolic extract of Shorea robusta resin in experimental animals.

Tariq Ahmad Wani, Dhirendra Kumar, Raju Prasad, Pawan Kumar Verma, Kaustuk K Sardar, Surendra Kumar Tandan, Dinesh Kumar

Open access · greenAbstract read
In one paragraph

Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Dipterocarpol in Oleoresin ofMolecules (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Antidiabetic, Antimicrobial, and Molecular Profiling of Selected Medicinal Plants.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  7. Article
  8. Article
  9. Studies on analgesic, anti-inflammatory activities of stem and roots ofJournal of traditional and complementary medicine · 2017
    Article
  10. Article
  11. Effect ofResearch in pharmaceutical sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tariq Ahmad WaniDivision of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar, UP, India.
Dhirendra Kumar
Raju Prasad
Pawan Kumar Verma
Kaustuk K Sardar
Surendra Kumar Tandan
Dinesh Kumar
Indian Veterinary Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimShorea robusta (Sal), an important traditional Indian medicinal plant used in various ailments and rituals and the indigenous use of the resin of this plant as a medicament for treatment of various inflammatory conditions is well documented in literature. In the present study, ethanolic extract of S. robusta resin (SRE) was evaluated for its analgesic activity by making use of different central and peripheral pain models. MATERIALS AND

methodsThe analgesic activity of SRE was assessed by employing different pain models such as, i) hot plate and tail flick tests for central analgesia, ii) acetic acid- induced writhing (peripheral analgesic model), iii) formalin-induced hind paw licking (both central and peripheral model), iv) carrageenan-induced hyperalgesia (peripheral analgesic model) and v) post-surgical pain (peripheral analgesic model).

resultsThe extract produced significant central and peripheral analgesic effects, as is evident from increase in reaction time in hot plate and tail flick tests, inhibition in writhing counts in acetic acid-induced writhing test, inhibition of licking time in formalin-induced hind paw licking, increased pain threshold in paw withdrawal latency in carrageenan-induced hyperalgesia and increased paw withdrawal threshold in post-surgical pain.

conclusionThe results of the present study demonstrate marked antinociceptive effects of SRE.

Indexed as

DipterocarpaceaeAnalgesicsAnimalsDisease Models, AnimalEthanolFemaleMicePainPain MeasurementPlant ExtractsRatsRats, WistarReaction TimeAnalgesicsEthanolPlant ExtractsCarrageenanhot platepost-surgical painresinShorea robustatail flick

Identifiers

PMID23087512
PMCPMC3469954
OpenAlexW2064334453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.