ArticleCancer prevention research (Philadelphia, Pa.)2012
Benign breast disease and the risk of subsequent breast cancer in African American women.
Article in Cancer prevention research (Philadelphia, Pa.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Guidelines for the clinical application of thePharmaceutical biology · 2024Guideline
- Breast Cancer Risk After Benign Breast Disease Among Racially Diverse Women: Systematic Review and Meta-Analysis.Research square · 2026Article
- Subsequent breast cancer risk after benign breast biopsy in racially diverse women: Siteman Cancer Center.Journal of the National Cancer Institute · 2026Article
- Research on the Anti-breast Hyperplasia Mechanism of Liqi Sanjie Granules Based on Network Pharmacological Analysis and Experimental Verification.Current drug targets · 2026Article
- Polygenic risk scores stratify breast cancer risk among women with benign breast disease.Journal of the National Cancer Institute · 2025Article
- A systematic review of determinants of breast cancer risk among women with benign breast disease.NPJ breast cancer · 2025Article
- Understanding Benign Breast Disease and Subsequent Breast Cancer in Hispanic White Females: A Step Closer to Evidence-Based Management.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Benign breast disease and breast cancer risk in African women: a case-control study.Cancer causes & control : CCC · 2024Article
- Benign Breast Disease and Breast Cancer Risk in the Percutaneous Biopsy Era.JAMA surgery · 2024Article
- Multiplicity of benign breast disease lesions and breast cancer risk in African American women.Frontiers in oncology · 2024Article
- Multi-MicroRNA Analysis Can Improve the Diagnostic Performance of Mammography in Determining Breast Cancer Risk.The breast journal · 2023Article
- Inflammation markers on benign breast biopsy are associated with risk of invasive breast cancer in African American women.Breast cancer research and treatment · 2021Article
- Acupuncture for mammary gland hyperplasia: A Bayesian network meta-analysis protocol.Medicine · 2020Article
- A longitudinal study of the prevalence and characteristics of breast disorders detected by clinical breast examination during pregnancy and six months postpartum in Ibadan, Southwestern Nigeria.BMC women's health · 2018Article
- Breast fibroadenomas are not associated with increased breast cancer risk in an African American contemporary cohort of women with benign breast disease.Breast cancer research : BCR · 2018Article
- Subtypes of Benign Breast Disease as a Risk Factor of Breast Cancer: A Systematic Review and Meta Analyses.Iranian journal of medical sciences · 2018Review
- Subtypes of Benign Breast Disease as a Risk Factor for Breast Cancer: A Systematic Review and Meta-Analysis Protocol.Iranian journal of medical sciences · 2018Article
- Association Between Benign Breast Disease in African American and White American Women and Subsequent Triple-Negative Breast Cancer.JAMA oncology · 2017Article
- Serum IGFBP-2 and Risk of Atypical Hyperplasia of the Breast.Journal of cancer epidemiology · 2015Article
- Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: a study from a population-based screening program.Breast cancer research and treatment · 2015Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 1 country.
Funding
Abstract
Benign breast disease (BBD) is an established risk factor for breast cancer among Caucasian women but less is known about BBD in African American women. As African American women suffer from disproportionate mortality due to breast cancer, special focus on pathologic characteristics that may influence disease risk is warranted. Benign breast biopsies from African American women were identified by the University Pathology Group (Detroit, MI). African American women of ages 20 to 84 years, who underwent a breast biopsy from 1997 to 2000, were eligible for the study. Subsequent breast cancers were identified through a linkage with the Detroit Surveillance Epidemiology and End Results (SEER) program. The first biopsy was reviewed by the pathologist, and lesions were classified following Dupont and Page criteria along with involution and other histologic features. Logistic regression was used to estimate the risk of developing a subsequent breast cancer with the histologic characteristics of BBD. A total of 1,406 BBD biopsies from African American women were included in this study with a median follow-up of 10.1 years. The majority (68%) showed nonproliferative disease, 29% had proliferative disease without atypia, and 3% had proliferative disease with atypia. Subsequent incident breast cancers occurred in 55 women (3.9%). Women whose biopsies showed proliferative disease with atypia were more than three-fold more likely to develop breast cancer as compared with women who had nonproliferative disease [relative risk (RR) 3.29, 95% confidence interval (CI) 1.21-8.93]. Better characterization of the risk of breast cancer among women with BBD, considering both ethnicity and detailed molecular findings, can lead to better surveillance, earlier diagnosis, and potentially improved survival.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.