SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2013
Systematic review reveals limitations of studies evaluating health-related quality of life after potentially curative treatment for esophageal cancer.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The impact of patient-reported outcome (PRO) data from clinical trials: a systematic review and critical analysis.Health and quality of life outcomes · 2019Pooled it
- Reporting of health-related quality of life in randomized controlled trials involving palliative systemic therapy for esophagogastric cancer: a systematic review.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2018Pooled it
- Meta-analysis shows clinically relevant and long-lasting deterioration in health-related quality of life after esophageal cancer surgery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Pooled it
- Meta-analysis shows clinically relevant and long-lasting deterioration in health-related quality of life after esophageal cancer surgery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Pooled it
- Patient-reported outcomes (PROs) in NRG Oncology RTOG 0436: a phase III trial evaluating the addition of cetuximab to paclitaxel, cisplatin, and radiation for esophageal cancer treated without surgery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Trial
- Patient-reported outcomes during and after definitive chemoradiotherapy for oesophageal cancer.British journal of cancer · 2015Trial
- Patient-reported outcomes following esophagectomy.Journal of thoracic disease · 2024Review
- Patient-reported gastrointestinal symptoms in gastric cancer after laparoscopic distal gastrectomy.Frontiers in oncology · 2024Article
- Quality of Life in Patients Undergoing Surgery for Upper GI Malignancies.Life (Basel, Switzerland) · 2023Review
- Choosing the right survey-patient reported outcomes in esophageal surgery.Journal of thoracic disease · 2020Review
- Contrast-enhanced computed tomography combined with Chitosan-FeExperimental and therapeutic medicine · 2018Article
- Quality of life assessment in esophagectomy patients.Annals of translational medicine · 2018Review
- Quality of life after esophageal resection.Patient related outcome measures · 2018Article
- Health-Related Quality of Life of Patients with Acute Myeloid Leukemia: A Systematic Literature Review.Oncology and therapy · 2017Review
- Developing core outcomes sets: methods for identifying and including patient-reported outcomes (PROs).Trials · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
purposeTo (1) assess the quality of studies evaluating Health-Related Quality of Life (HRQL) after potentially curative treatment for esophageal cancer, and (2) to identify high-quality studies that provide robust HRQL results.
methodsA systematic literature search is to identify studies evaluating HRQL with a validated multidimensional patient-reported outcome measure. Study quality focused on study design, risk of bias, HRQL outcome reporting, and additional issues of reporting and methodology. A study was deemed high-quality if criteria for robust study methodology and robust HRQL outcome reporting were met.
resultsSix RCTs, 12 cohort studies, 13 case-series, and 31 cross-sectional studies were identified. Overall risk of bias was high. Reporting of HRQL concept (e.g., a priori hypothesis), methodology (e.g., reasons for missing data), and interpretation (e.g., clinical significance) was often absent or unclear. Additional issues of reporting (e.g., unclear treatment descriptions) and methodology (e.g., no control for multiple testing) were identified. Four studies (6%) met the criteria for robust study methodology, and 26 studies (42%) met the criteria for robust HRQL outcome reporting. We identified three high-quality studies (5%)--two RCTs and one case-series--capable of providing robust results.
conclusionsCurrent evidence is restricted in its ability to inform practice on HRQL after potentially curative treatment for esophageal cancer.
Indexed as
Identifiers
23086534What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.