ArticleGenome research2012
Complementation contributes to transcriptome complexity in maize (Zea mays L.) hybrids relative to their inbred parents.
Article in Genome research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.
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Who cites it
96 citing papers in PubMed.
- A novel genetic framework reveals transcriptional "butterfly effect" underlying heterosis in maize.Journal of advanced research · 2026Article
- Chromatin accessibility landscape and its association with heterosis in maize hybrids.Nature communications · 2026Article
- Expression heterosis in the abaca (Musa textilis Née) BCBMC genomics · 2026Article
- Quantitative Insights into the Genetic Mechanisms of Crop Heterosis.Advanced genetics (Hoboken, N.J.) · 2025Review
- Conservation and variability of long-range interactions in structurally diverse maize genomes.Nature communications · 2025Article
- Genetic Resources of Cereal and Oilseed Crops for Heterotic Hybrid Breeding.Plants (Basel, Switzerland) · 2025Review
- Regulation of heterosis-associated gene expression complementation in maize hybrids.Genome biology · 2025Article
- Nonadditive gene expression contributing to heterosis in partially heterozygous maize hybrids is predominantly regulated from heterozygous regions.The New phytologist · 2025Article
- Transcripts and genomic intervals associated with variation in metabolite abundance in maize leaves under field conditions.BMC genomics · 2025Article
- Impact of Allele-Specific Expression on Ripening and Quality Characteristics of ABB Banana Fruit.International journal of molecular sciences · 2025Article
- Haplotype-resolved T2T genome assemblies and pangenome graph of pear reveal diverse patterns of allele-specific expression and the genomic basis of fruit quality traits.Plant communications · 2024Article
- Hybrid Prediction in Horticulture Crop Breeding: Progress and Challenges.Plants (Basel, Switzerland) · 2024Review
- Non-additive expression genes play a critical role in leaf vein ratio heterosis in Nicotiana tabacum L.BMC genomics · 2024Article
- Dynamic relationships among pathways producing hydrocarbons and fatty acids of maize silk cuticular waxes.Plant physiology · 2024Article
- High-quality genome assembly enables prediction of allele-specific gene expression in hybrid poplar.Plant physiology · 2024Article
- Strand-Specific RNA Sequencing Reveals Gene Expression Patterns in F1 Chick Breast Muscle and Liver after Hatching.Animals : an open access journal from MDPI · 2024Article
- Review
- Study on Allele Specific Expression of Long-Term Residents in High Altitude Areas.Evolutionary bioinformatics online · 2024Article
- Pervasive under-dominance in gene expression underlying emergent growth trajectories in Arabidopsis thaliana hybrids.Genome biology · 2023Article
- Molecular dissection of heterosis in cereal roots and their rhizosphere.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Review
36 more citing papers are in PubMed but not listed here.
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Typically, F(1)-hybrids are more vigorous than their homozygous, genetically distinct parents, a phenomenon known as heterosis. In the present study, the transcriptomes of the reciprocal maize (Zea mays L.) hybrids B73×Mo17 and Mo17×B73 and their parental inbred lines B73 and Mo17 were surveyed in primary roots, early in the developmental manifestation of heterotic root traits. The application of statistical methods and a suitable experimental design established that 34,233 (i.e., 86%) of all high-confidence maize genes were expressed in at least one genotype. Nearly 70% of all expressed genes were differentially expressed between the two parents and 42%-55% of expressed genes were differentially expressed between one of the parents and one of the hybrids. In both hybrids, ∼10% of expressed genes exhibited nonadditive gene expression. Consistent with the dominance model (i.e., complementation) for heterosis, 1124 genes that were expressed in the hybrids were expressed in only one of the two parents. For 65 genes, it could be shown that this was a consequence of complementation of genomic presence/absence variation. For dozens of other genes, alleles from the inactive inbred were activated in the hybrid, presumably via interactions with regulatory factors from the active inbred. As a consequence of these types of complementation, both hybrids expressed more genes than did either parental inbred. Finally, in hybrids, ∼14% of expressed genes exhibited allele-specific expression (ASE) levels that differed significantly from the parental-inbred expression ratios, providing further evidence for interactions of regulatory factors from one parental genome with target genes from the other parental genome.
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