Evidence map›Paper›PMID 23085859›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2013

Mediterranean diet and incidence of hip fractures in a European cohort.

V Benetou, P Orfanos, U Pettersson-Kymmer, U Bergström, O Svensson, I Johansson, F Berrino, R Tumino, K B Borch, E Lund and 11 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 11 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 11 syntheses or guidelines pooled it, 139 citations in OpenAlex.

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  7. Dietary vitamin C intake and the risk of hip fracture: a dose-response meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
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  11. Alcohol consumption and hip fracture risk.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 9 countries.

V BenetouWHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 Mikras Asias street, 115 27 Athens, Greece. vben@nut.uoa.gr
P Orfanos
U Pettersson-Kymmer
U Bergström
O Svensson
I Johansson
F Berrino
R Tumino
K B Borch
E Lund
P H M Peeters
V Grote
K Li
J M Altzibar
T Key
H Boeing
A von Ruesten
T Norat
P A Wark
E Riboli
A Trichopoulou
St Mary's Hospital · GBUmeå University · SENational and Kapodistrian University of Athens · GRGerman Institute of Human Nutrition · DEUiT The Arctic University of Norway · NOAzienda Usl 8 Arezzo · ITCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESFondazione IRCCS Istituto Nazionale dei Tumori · ITGerman Cancer Research Center · DEHeidelberg University · DEUniversity of Oxford · GB

Funding

Cancer Research UK
6 · The paper itself

Abstract

unlabelledPrevention of hip fractures is of critical public health importance. In a cohort of adults from eight European countries, evidence was found that increased adherence to Mediterranean diet, measured by a 10-unit dietary score, is associated with reduced hip fracture incidence, particularly among men.

introductionEvidence on the role of dietary patterns on hip fracture incidence is scarce. We explored the association of adherence to Mediterranean diet (MD) with hip fracture incidence in a cohort from eight European countries.

methodsA total of 188,795 eligible participants (48,814 men and 139,981 women) in the European Prospective Investigation into Cancer and nutrition study with mean age 48.6 years (±10.8) were followed for a median of 9 years, and 802 incident hip fractures were recorded. Diet was assessed at baseline through validated dietary instruments. Adherence to MD was evaluated by a MD score (MDs), on a 10-point scale, in which monounsaturated were substituted with unsaturated lipids. Association with hip fracture incidence was assessed through Cox regression with adjustment for potential confounders.

resultsIncreased adherence to MD was associated with a 7 % decrease in hip fracture incidence [hazard ratio (HR) per 1-unit increase in the MDs 0.93; 95 % confidence interval (95 % CI) = 0.89-0.98]. This association was more evident among men and somewhat stronger among older individuals. Using increments close to one standard deviation of daily intake, in the overall sample, high vegetable (HR = 0.86; 95 % CI = 0.79-0.94) and high fruit (HR = 0.89; 95 % CI = 0.82-0.97) intake was associated with decreased hip fracture incidence, whereas high meat intake (HR = 1.18; 95 % CI = 1.06-1.31) with increased incidence. Excessive ethanol consumption (HR high versus moderate = 1.74; 95 % CI = 1.32-2.31) was also a risk factor.

conclusionsIn a prospective study of adults, increased adherence to MD appears to protect against hip fracture occurrence, particularly among men.

Indexed as

AdultAgedAge FactorsCohort StudiesDiet, MediterraneanEuropeFeeding BehaviorFemaleHip FracturesHumansIncidenceLife StyleMaleMiddle AgedProspective StudiesSex Factors

Identifiers

PMID23085859
OpenAlexW2057329398

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.