ReviewAdvances in genetics2012
The genetic analysis of functional connectomics in Drosophila.
Review in Advances in genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Endocrine cybernetics: neuropeptides as molecular switches in behavioural decisions.Open biology · 2022Review
- Building a circuit through correlated spontaneous neuronal activity in the developing vertebrate and invertebrate visual systems.Genes & development · 2021Review
- Genetic Transsynaptic Techniques for Mapping Neural Circuits inFrontiers in neural circuits · 2021Review
- Cellular and synaptic adaptations of neural circuits processing skylight polarization in the fly.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020Article
- Stochastic and Arbitrarily Generated Input Patterns to the Mushroom Bodies Can Serve as Conditioned Stimuli inFrontiers in physiology · 2020Article
- A resource for theeLife · 2018Article
- Tracing neuronal circuits in transgenic animals by transneuronal control of transcription (eLife · 2017Article
- Review
- Micro-connectomics: probing the organization of neuronal networks at the cellular scale.Nature reviews. Neuroscience · 2017Review
- Monitoring cell-cell contacts in vivo in transgenic animals.Development (Cambridge, England) · 2016Article
- Aversive Behavior in the Nematode C. elegans Is Modulated by cGMP and a Neuronal Gap Junction Network.PLoS genetics · 2016Article
- Synaptic circuitry of identified neurons in the antennal lobe of Drosophila melanogaster.The Journal of comparative neurology · 2016Article
- What genetic model organisms offer the study of behavior and neural circuits.Journal of neurogenetics · 2016Review
- Dynamic labelling of neural connections in multiple colours by trans-synaptic fluorescence complementation.Nature communications · 2015Article
- A common evolutionary origin for the ON- and OFF-edge motion detection pathways of the Drosophila visual system.Frontiers in neural circuits · 2015Article
- Candidate neural substrates for off-edge motion detection in Drosophila.Current biology : CB · 2014Article
- Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- A hard-wired glutamatergic circuit pools and relays UV signals to mediate spectral preference in Drosophila.Neuron · 2014Article
- Segmentation of the mouse fourth deep lumbrical muscle connectome reveals concentric organisation of motor units.The Journal of physiology · 2013Article
- From the connectome to brain function.Nature methods · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Fly and vertebrate nervous systems share many organizational features, such as layers, columns and glomeruli, and utilize similar synaptic components, such as ion channels and receptors. Both also exhibit similar network features. Recent technological advances, especially in electron microscopy, now allow us to determine synaptic circuits and identify pathways cell-by-cell, as part of the fly's connectome. Genetic tools provide the means to identify synaptic components, as well as to record and manipulate neuronal activity, adding function to the connectome. This review discusses technical advances in these emerging areas of functional connectomics, offering prognoses in each and identifying the challenges in bridging structural connectomics to molecular biology and synaptic physiology, thereby determining fundamental mechanisms of neural computation that underlie behavior.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.