Evidence map›Paper›PMID 23084280›Full record

Trial reportDiabetes research and clinical practice2012

Improving diabetes care: multi-component cardiovascular disease risk reduction strategies for people with diabetes in South Asia--the CARRS multi-center translation trial.

CARRS Trial Writing Group, Seema Shah, Kavita Singh, Mohammed K Ali, V Mohan, Muhammad Masood Kadir, A G Unnikrishnan, Rakesh Kumar Sahay, Premlata Varthakavi, Mala Dharmalingam and 12 more

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes research and clinical practice, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01212328 naunknown statusnot on this map

Developing and Testing Integrated, Multi-factorial Cardiovascular Disease Risk Reduction Strategies in South Asia (CARRS Translation Trial)

TypeinterventionalSponsorPublic Health Foundation of IndiaRan2010 to 2014Enrolled1,120ConditionsType 2 Diabetes Mellitus, Hypertension, DyslipidaemiaArmsCare Coordinator + Decision Support Software, Usual care
NCT02022111 nacompletednot on this mapstarted 2014, after this paper: background citation

INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) Study

TypeinterventionalSponsorEmory UniversityRan2014 to 2019Enrolled404ConditionsDiabetes, Depression, Cardiovascular Risk FactorArmsPatient Education and Behavioral Activation, Supporting Self-Care (care coordinators), Psychiatrist and Diabetologist Reviews, Decision-support Electronic Health Record System, Standard of Care
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024
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  3. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017
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  4. Risk scoring for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 14 institutions in 3 countries.

CARRS Trial Writing GroupEmory University, Rollins School of Public Health, Atlanta, GA 30322, USA.
Seema Shah
Kavita Singh
Mohammed K Ali
V Mohan
Muhammad Masood Kadir
A G Unnikrishnan
Rakesh Kumar Sahay
Premlata Varthakavi
Mala Dharmalingam
Vijay Viswanathan
Qamar Masood
Ganapathi Bantwal
Rajesh Khadgawat
Ankush Desai
Bipin Kumar Sethi
Roopa Shivashankar
Vamadevan S Ajay
K Srinath Reddy
K M Venkat Narayan
Dorairaj Prabhakaran
Nikhil Tandon
Public Health Foundation of India · INEmory University · USAga Khan University · PKAll India Institute of Medical Sciences · INAmrita Institute of Medical Sciences and Research Centre · INBangalore Diabetes Centre · INCARE Hospitals · INCentre for Chronic Disease Control · INGoa Medical College · INMadras Diabetes Research Foundation · INM.V. Hospital for Diabetes and Diabetes Research Centre · INOsmania General Hospital · INSt.John's Medical College Hospital · INTopiwala National Medical College & BYL Nair Charitable Hospital · IN

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
FIC NIH HHS 5R24TW007988FIC NIH HHS R24 TW007988NHLBI NIH HHS HHSN268200900026C
6 · The paper itself

Abstract

aimsCardiovascular disease (CVD) is the leading cause of morbidity and mortality in people with diabetes in South Asia. The CARRS Translation Trial tests the effectiveness, cost-effectiveness, and sustainability of a clinic-based multi-component CVD risk reduction intervention among people with diabetes in India and Pakistan.

methodsWe randomly assigned 1146 adults with diabetes recruited from 10 urban clinic sites, to receive usual care by physicians or to receive an integrated multi-component CVD risk reduction intervention. The intervention involves electronic health record management, decision-support prompts to the healthcare team, and the support of a care coordinator to actively facilitate patient and provider adherence to evidence-based guidelines. The primary outcome is a composite of multiple CVD risk factor control (blood glucose and either blood pressure or cholesterol, or all three). Other outcomes include control of the individual CVD risk factors, process and patient-centered measures, cost-effectiveness, and acceptability/feasibility.

conclusionThe CARRS Translation Trial tests a low-cost diabetes care delivery model in urban South Asia to achieve comprehensive cardio-metabolic disease case-management of high-risk patients (clinicaltrials.gov number: NCT01212328).

Indexed as

AdultAsiaCardiovascular DiseasesCost-Benefit AnalysisDiabetes Mellitus, Type 2HumansRisk Reduction BehaviorSoftware

Identifiers

PMID23084280
PMCPMC3544938
OpenAlexW1968579605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.