ArticleThe Journal of urology2012
Outcomes of patients with surgically treated bilateral renal masses and a minimum of 10 years of followup.
Article in The Journal of urology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- NCCN Guidelines Insights: Kidney Cancer, Version 1.2021.Journal of the National Comprehensive Cancer Network : JNCCN · 2020Guideline
- Familial Kidney Cancer: Implications of New Syndromes and Molecular Insights.European urology · 2019Pooled it
- Renal surgery following HIF-2α antagonist therapy: Surgical indications, outcomes and growth kinetics.Urologic oncology · 2025Article
- Outcomes of and indications for renal transplantation in patients with von Hippel Lindau disease.Urologic oncology · 2023Article
- A 25 year perspective on the evolution and advances in an understanding of the biology, evaluation and treatment of kidney cancer.Urologic oncology · 2021Review
- Article
- Evaluation of functional outcome of bilateral kidney tumors after sequential surgery.BMC cancer · 2021Article
- Surgical strategy of bilateral synchronous sporadic renal cell carcinoma-experience of a Chinese university hospital.World journal of surgical oncology · 2017Article
- Re: Csaba Berczi, Ben Thomas, Zsolt Bacso, Tibor Flasko. Bilateral renal cancers: oncological and functional outcomes. Int Urol Nephrol 2016 (Epub ahead of print).International urology and nephrology · 2017Article
- Treatment of Multifocal Renal Cell Carcinoma in a Solitary Kidney With Nivolumab.Clinical genitourinary cancer · 2017Article
- What is the Optimal Management Strategy for Multifocal and Hereditary Kidney Cancer?Journal of renal medicine · 2017Article
- Multiplex Partial Nephrectomy, Repeat Partial Nephrectomy, and Salvage Partial Nephrectomy Remain the Primary Treatment in Multifocal and Hereditary Kidney Cancer.Frontiers in oncology · 2017Review
- Bilateral renal cancers: oncological and functional outcomes.International urology and nephrology · 2016Article
- Bilateral Multi-Focal Sporadic Papillary Renal Cell Carcinoma: A Unique Surgical Challenge.Journal of clinical and diagnostic research : JCDR · 2016Article
- Cross-talk between tumors can affect responses to therapy.Oncoimmunology · 2015Article
- Renal cell carcinoma in young patients: a review of recent literature.Current urology reports · 2015Review
- Implications of Von Hippel-Lindau Syndrome and Renal Cell Carcinoma.Journal of kidney cancer and VHL · 2015Article
- Nephron-sparing surgery for multifocal and hereditary renal tumors.Current opinion in urology · 2014Review
- Bilateral synchronous sporadic renal masses: intermediate functional and oncological outcomes at a single institution.International urology and nephrology · 2013Article
- Surgical Insights for the Management of Variant Histology in Renal Cell Carcinoma.International braz j urol : official journal of the Brazilian Society of UrologyReview
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
purposeNephron sparing surgery has been advocated for patients with bilateral renal masses but long-term functional and oncological outcomes are lacking. We report the outcomes of patients with bilateral renal masses and a minimum 10-year followup. MATERIALS AND
methodsPatients with bilateral renal masses evaluated at our institution who were treated with initial surgery at least 10 years ago and underwent interventions on each renal unit were included in the analysis. Collected data included demographics, hereditary diagnosis, number of renal interventions, renal function and mortality status. Overall and renal cell carcinoma specific survival was assessed. Comparisons were made of renal function and overall survival between groups with 2 renal units and a surgically solitary kidney.
resultsA total of 128 patients met study inclusion criteria. Median followup in our cohort was 16 years (mean 17, range 10 to 49). The median number of surgical interventions was 3 (range 2 to 10). Of the patients 87 (68%) required repeat interventions on the ipsilateral renal unit at last followup with a median of 6.2 years (range 0.7 to 21) between interventions. Overall and renal cell cancer specific survival was 88% and 97%, respectively. Six patients (4.7%) ultimately underwent bilateral nephrectomy. Although renal function was better preserved in patients with 2 kidneys (70 vs 53 ml/minute/1.73 m(2), p = 0.0002), there was no difference in overall survival between those with bilateral kidneys or a surgically solitary kidney.
conclusionsAt a minimum 10-year followup after initial surgery, nephron sparing surgery allowed for excellent oncological and functional outcomes. Despite the need for repeat surgical interventions, nephron sparing surgery enabled dialysis to be avoided in more than 95% of patients.
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