ArticleBiophysical journal2012
Increasing membrane tension decreases miscibility temperatures; an experimental demonstration via micropipette aspiration.
Article in Biophysical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Electrodeformation of DMPC vesicle membranes near the main phase transition.Biophysical journal · 2025Article
- Sterol-lipids enable large-scale, liquid-liquid phase separation in bilayer membranes of only two components.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Coupling liquid phases in 3D condensates and 2D membranes: Successes, challenges, and tools.Biophysical journal · 2024Review
- Methyl-β-cyclodextrin asymmetrically extracts phospholipid from bilayers, granting tunable control over differential stress in lipid vesicles.Soft matter · 2024Article
- RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding.Chemical reviews · 2024Review
- Remodeling of yeast vacuole membrane lipidomes from the log (one phase) to stationary stage (two phases).Biophysical journal · 2023Article
- Methods to mechanically perturb and characterize GUV-based minimal cell models.Computational and structural biotechnology journal · 2023Review
- Fluid-gel coexistence in lipid membranes under differential stress.Biophysical journal · 2022Article
- Systematic measurements of interleaflet friction in supported bilayers.Biophysical journal · 2022Article
- Micropipette-based biomechanical nanotools on living cells.European biophysics journal : EBJ · 2022Review
- Intelligent fluorescence image analysis of giant unilamellar vesicles using convolutional neural network.BMC bioinformatics · 2022Article
- Polymer-Lipid Hybrid Materials.Chemical reviews · 2021Review
- Superelasticity of Plasma- and Synthetic Membranes Resulting from Coupling of Membrane Asymmetry, Curvature, and Lipid Sorting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- EPA and DHA differentially modulate membrane elasticity in the presence of cholesterol.Biophysical journal · 2021Article
- Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids.Science advances · 2021Article
- Imaging non-classical mechanical responses of lipid membranes using molecular rotors.Chemical science · 2020Article
- Principles and Applications of Biological Membrane Organization.Annual review of biophysics · 2020Review
- Plasma membrane tension regulates eisosome structure and function.Molecular biology of the cell · 2020Article
- Observations of Membrane Domain Reorganization in Mechanically Compressed Artificial Cells.Chembiochem : a European journal of chemical biology · 2019Article
- The plasma membrane as a mechanochemical transducer.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
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Authors and funding
3 authors.
Funding
Abstract
It has been hypothesized that cytoskeletal tension prevents large-scale phase separation within cell plasma membranes. Here, we microaspirate giant unilamellar vesicles to determine the effect of mechanical stress on the liquid/liquid miscibility temperature of a membrane composed of a ternary lipid mixture. An increase in tension of 0.1 mN/m induces a decrease in miscibility temperature on the order of a few tenths of a degree K, which validates recent theoretical predictions.
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Registered trials
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