Evidence map›Paper›PMID 23083638›Full record

ArticleDiagnostic microbiology and infectious disease2013

Evaluation of the specificity and sensitivity of a potential rapid influenza screening system.

Luis E Perez, Gerald A Merrill, Robert A DeLorenzo, Thomas W Schoenfeld, Abhay Vats, Michael J Moser

Abstract readEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Molecular oncology testing in resource-limited settings.The Journal of molecular diagnostics : JMD · 2014
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luis E PerezDepartment of Clinical Investigation, Brooke Army Medical Center, Ft. Sam Houston, TX 78234-6315, USA. Luis.Perez2@amedd.army.mil
Gerald A Merrill
Robert A DeLorenzo
Thomas W Schoenfeld
Abhay Vats
Michael J Moser

Funding

Point of Care Detection of Respiratory VirusesR44AI081467 · NIAID · LUCIGEN CORPORATION · PI SCHOENFELD, THOMAS WILLIAM · 2012 to 2014
$2.7M
Point of care detection of respiratory virusesR43AI081467 · NIAID · LUCIGEN CORPORATION · PI SCHOENFELD, THOMAS WILLIAM, VATS, ABHAY N. · 2009 to 2009
$300k
NIAID NIH HHS R43 AI081467
6 · The paper itself

Abstract

Influenza remains a serious worldwide health threat with numerous deaths attributed to influenza-related complications. It is likely that transmission of influenza and both the morbidity and mortality of influenza could be reduced if inexpensive but reliable influenza screening assays were more available to the general public or local medical treatment facilities. This report provides the initial evaluation of a pilot system designed by Lucigen Corp. (Middleton, WI, USA) as a potential rapid near point-of-care screening system for influenza A and influenza B. The evaluation of specificity and sensitivity was conducted on stored nasal swab samples collected from emergency department patients presenting with influenza-like symptoms at a large military academic hospital and on de-identified nasal swabs and isolated RNA from a local epidemiology laboratory. The gold standard for assessment of specificity and sensitivity was the Luminex® Respiratory Viral Panel.

Indexed as

Clinical Laboratory TechniquesHumansInfluenza A virusInfluenza B virusInfluenza, HumanMass ScreeningNasal MucosaPoint-of-Care SystemsSensitivity and SpecificityUnited StatesVirology

Identifiers

PMID23083638
PMCPMC7132696

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.