Trial reportInternational psychogeriatrics2013
Longitudinal relationships between subjective fatigue, cognitive function, and everyday functioning in old age.
Trial report in International psychogeriatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00298558 (Trial of a Cognitive Intervention for Older Adults), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Trial of a Cognitive Intervention for Older Adults
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study.AIDS and behavior · 2024Trial
- Trial
- Disentangling the association of depression on the anti-fatigue effects of ketamine.Journal of affective disorders · 2019Trial
- Nonlinear relationships between fatigue, fear of COVID-19, and PTSD among mental health professionals: the findings of a multi-site survey in China.Frontiers in psychiatry · 2026Article
- Effective engagement in computerized cognitive training for older adults.Ageing research reviews · 2025Review
- Prolonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors.Journal of clinical and translational science · 2025Article
- Fatigue in Alzheimer's disease: biological basis and clinical management-a narrative review.Aging clinical and experimental research · 2023Review
- Clinical Significance of Physical Frailty in Subjects With Subjective Cognitive Decline: A Prospective Study With Amyloid PET Data.Journal of clinical neurology (Seoul, Korea) · 2023Article
- Early and Persistent Dysphagia Relief Predicts Tumor Response in Esophageal Squamous Cell Carcinoma Patients Treated with Immunochemotherapy.Annals of surgical oncology · 2023Article
- Association between cardiopulmonary function, health-related quality of life and cognitive impairment among the older nursing home residents in Shanghai, China.Primary health care research & development · 2023Article
- A Multi-Dimensional Model of Fatigue in Old Age: Implications for Brain Aging.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023Article
- Brain Small-Worldness Properties and Perceived Fatigue in Mild Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Combined effects of older age and HIV disease on changes in everyday functioning over one year.Journal of neurovirology · 2022Article
- Article
- Physical Frailty Phenotype Criteria and Their Synergistic Association on Cognitive Functioning.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- Adult Age Differences in the Effects of Chronic Mental Fatigue on Task-Related Fatigue, Appraisals, and Performance.Motivation science · 2021Article
- The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline.Neuro-degenerative diseases · 2021Review
- Longitudinal Association Between Perceived Fatigability and Cognitive Function in Older Adults: Results from the Baltimore Longitudinal Study of Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Co-occuring symptoms in older oncology patients with distinct attentional function profiles.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThe present study examined the prospective relationships between subjective fatigue, cognitive function, and everyday functioning.
methodsA cohort study with secondary data analysis was conducted using data from 2,781 community-dwelling older adults without dementia who were enrolled to participate in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) randomized intervention trial. Measures included demographic and health information at baseline, and annual assessments of subjective fatigue, cognitive function (i.e. speed of processing, memory, and reasoning), and everyday functioning (i.e. everyday speed and everyday problem-solving) over five years.
resultsFour distinct classes of subjective fatigue were identified using growth mixture modeling: one group complaining fatigue "some of the time" at baseline but "most of the time" at five-year follow-up (increased fatigue), one complaining fatigue "a good bit of the time" constantly over time (persistent fatigue), one complaining fatigue "most of the time" at baseline but "some of the time" at five-year follow-up (decreased fatigue), and the fourth complaining fatigue "some of the time" constantly over time (persistent energy). All domains of cognitive function and everyday functioning declined significantly over five years; and the decline rates, but not the baseline levels, differed by the latent class of subjective fatigue. Except for the decreased fatigue class, there were different degrees of significant associations between the decline rates of subjective fatigue and all domains of cognitive function and everyday functioning in other classes of subjective fatigue.
conclusionFuture interventions should address subjective fatigue when managing cognitive and functional abilities in community-dwelling older adults.
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Registered trials
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