Evidence map›Paper›PMID 23082162›Full record

ArticlePloS one2012

Safety of over twelve hundred infant male circumcisions using the Mogen clamp in Kenya.

Marisa R Young, Robert C Bailey, Elijah Odoyo-June, Tracy E Irwin, Walter Obiero, Dedan O Ongong'a, Jacinta A Badia, Kawango Agot, Sherry K Nordstrom

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03338699 (Evaluation of the ShangRing vs. Mogen Clamp for Early Infant Male Circumcision), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03338699 nacompletednot on this mapstarted 2018, after this paper: background citation

Evaluation of the ShangRing vs. Mogen Clamp for Early Infant Male Circumcision (EIMC) in Sub-Saharan Africa

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2018 to 2020Enrolled1,380ConditionsCircumcisionArmsShangRing, Mogen clamp
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  7. Single-arm evaluation of the AccuCirc device for early infant male circumcision in Botswana.Journal of acquired immune deficiency syndromes (1999) · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Marisa R YoungDepartment of Epidemiology and Biostatistics, University of Illinois at Chicago School of Public Health, Chicago, Illinois, USA. myoung22@uic.edu
Robert C Bailey
Elijah Odoyo-June
Tracy E Irwin
Walter Obiero
Dedan O Ongong'a
Jacinta A Badia
Kawango Agot
Sherry K Nordstrom
University of Illinois Chicago · USNyanza Reproductive Health Society · KEImpact Research and Development Organization · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral sub-Saharan African countries plan to scale-up infant male circumcision (IMC) for cost-efficient HIV prevention. Little data exist about the safety of IMC in East and southern Africa. We calculated adverse event (AE) rate and risks for AEs associated with introduction of IMC services at five government health facilities in western Kenya.

methodsAE data were analyzed for IMC procedures performed between September, 2009 and November, 2011. Healthy infants aged ≤ 2 months and weighing ≥ 2.5 kg were eligible for IMC. Following parental consent, trained clinicians provided IMC services free of charge under local anesthesia using the Mogen clamp. Odds ratios and 95% confidence intervals were used to explore AE risk factors.

findingsA total of 1,239 IMC procedures were performed. Median age of infants was 4 days (IQR=1, 16). The overall AE rate among infants reviewed post-operatively was 2.7% (18/678; 95%CI: 1.4, 3.9). There was one severe AE involving excision of a small piece of the lateral aspect of the glans penis. Other AEs were mild or moderate and were treated conservatively. Babies one month of age or older were more likely to have an AE (OR 3.20; 95%CI: 1.23, 8.36). AE rate did not differ by nurse versus clinical officer or number of previous procedures performed.

conclusionIMC services provided in Kenyan Government hospitals in the context of routine IMC programming have AE rates comparable to those in developed countries. The optimal time for IMC is within the first month of life.

Indexed as

Circumcision, MaleHumansInfant, NewbornKenyaMaleRisk FactorsSurgical Instruments

Identifiers

PMID23082162
PMCPMC3474828
OpenAlexW1963885880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.