ArticlePloS one2012
Prion remains infectious after passage through digestive system of American crows (Corvus brachyrhynchos).
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 54 citations in OpenAlex.
- White-tailed deer scavenging community in a chronic wasting disease-endemic region and considerations for prion movement.Scientific reports · 2026Article
- Prevalence of Toxocara cati and the Role of Wild Birds as Paratenic Hosts: First Evidence from Türkiye.Acta parasitologica · 2026Article
- Assessment of Mammalian Scavenger and Wild White-Tailed Deer Activity at White-Tailed Deer Farms.Viruses · 2025Article
- Global decline of apex scavengers threatens human health.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- On the underappreciated role of scavengers in freshwater ecosystems.Bioscience · 2025Review
- Distribution of chronic wasting disease (CWD) prions in tissues from experimentally exposed coyotes (Canis latrans).PloS one · 2025Article
- Prion forensics: a multidisciplinary approach to investigate CWD at an illegal deer carcass disposal site.Prion · 2024Article
- Retention of prions in the polychaeteHeliyon · 2024Article
- Detection of prions from spiked and free-ranging carnivore feces.Scientific reports · 2024Article
- Nasal bots carry relevant titers of CWD prions in naturally infected white-tailed deer.EMBO reports · 2024Article
- Integrating terrestrial scavenging ecology into contemporary wildlife conservation and management.Ecology and evolution · 2022Review
- Prion Dissemination through the Environment and Medical Practices: Facts and Risks for Human Health.Clinical microbiology reviews · 2021Review
- Chronic Wasting Disease Transmission Risk Assessment for Farmed Cervids in Minnesota and Wisconsin.Viruses · 2021Article
- Detection of Pathognomonic Biomarker PrPBiomolecules · 2020Review
- Efficient prion disease transmission through common environmental materials.The Journal of biological chemistry · 2018Article
- The Ecology of Prions.Microbiology and molecular biology reviews : MMBR · 2017Review
- The Development of a Novel qPCR Assay-Set for Identifying Fecal Contamination Originating from Domestic Fowls and Waterfowl in Israel.Frontiers in microbiology · 2016Article
- CWD prions remain infectious after passage through the digestive system of coyotes (Canis latrans).Prion · 2015Article
- Procedures for identifying infectious prions after passage through the digestive system of an avian species.Journal of visualized experiments : JoVE · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Avian scavengers, such as American crows (Corvus brachyrhynchos), have potential to translocate infectious agents (prions) of transmissible spongiform encephalopathy (TSE) diseases including chronic wasting disease, scrapie, and bovine spongiform encephalopathy. We inoculated mice with fecal extracts obtained from 20 American crows that were force-fed material infected with RML-strain scrapie prions. These mice all evinced severe neurological dysfunction 196-231 d postinoculation (x =198; 95% CI: 210-216) and tested positive for prion disease. Our results suggest a large proportion of crows that consume prion-positive tissue are capable of passing infectious prions in their feces (ˆp=1.0; 95% CI: 0.8-1.0). Therefore, this common, migratory North American scavenger could play a role in the geographic spread of TSE diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.