ArticleBMJ (Clinical research ed.)2012
Calcium intake and risk of primary hyperparathyroidism in women: prospective cohort study.
Article in BMJ (Clinical research ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Body Size and the Risk of Primary Hyperparathyroidism in Women: A Cohort Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017Trial
- Parathyroid Hormone and the Use of Diuretics and Calcium-Channel Blockers: The Multi-Ethnic Study of Atherosclerosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016Trial
- Some cases of primary hyperparathyroidism may not be truly primary in origin.Frontiers in endocrinology · 2026Review
- Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes.Endocrine reviews · 2025Review
- Dietary calcium intake in primary hyperparathyroidism and in its normocalcemic variant: a case-control study.Frontiers in endocrinology · 2024Article
- [Registries of parathyroid glands diseases in the Russian Federation].Problemy endokrinologii · 2021Article
- [Asymptomatic primary hyperparathyroidism : Operation or observation?]Der Internist · 2021Review
- Primary Hyperparathyroidism: A Narrative Review of Diagnosis and Medical Management.Journal of clinical medicine · 2021Review
- Evaluation of Serum Level of FGF23 and 1,25(OH)International journal of general medicine · 2020Article
- Primary Hyperparathyroidism.The Journal of clinical endocrinology and metabolism · 2018Review
- Primary hyperparathyroidism.Nature reviews. Endocrinology · 2018Review
- Calcium intake: good for the bones but bad for the heart? An analysis of clinical studies.Archives of endocrinology and metabolism · 2016Review
- Physical Activity and the Risk of Primary Hyperparathyroidism.The Journal of clinical endocrinology and metabolism · 2016Article
- Hypertension, Antihypertensive Medications, and Risk of Incident Primary Hyperparathyroidism.The Journal of clinical endocrinology and metabolism · 2015Article
- Secular trends in the incidence of primary hyperparathyroidism over five decades (1965-2010).Bone · 2015Article
- [Localization of parathyroid adenomas with C11-methionine PET-CT].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2014Review
- Calcium revisited: part I.BoneKEy reports · 2013Article
- Calcium and vitamin D intake and mortality: results from the Canadian Multicentre Osteoporosis Study (CaMos).The Journal of clinical endocrinology and metabolism · 2013Article
- A higher calcium intake reduces risk of primary hyperparathyroidism in women.BoneKEy reports · 2013Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo examine the association between calcium intake and risk of primary hyperparathyroidism in women.
designProspective cohort study.
settingNurses' Health Study I, which originally recruited participants from the 11 most populous states in the United States.
participants58,354 female registered nurses enrolled in the Nurses' Health Study I aged 39-66 years in 1986 and with no history of primary hyperparathyroidism. Calcium intake was assessed every four years using semiquantitative questionnaires on food frequency.
main outcome measureIncident primary hyperparathyroidism, confirmed by medical record review.
resultsDuring 22 years of follow-up, we recorded 277 incident cases of primary hyperparathyroidism. Women were divided into five equal groups, according to intake of dietary calcium. After adjusting for age, body mass index, race, and other factors, the relative risk of primary hyperparathyroidism for women in the group with the highest intake of dietary calcium was 0.56 (95% confidence interval 0.37 to 0.86, P=0.009 for trend), compared with the group with the lowest intake. The multivariable relative risk of primary hyperparathyroidism for women taking more than 500 mg/day of calcium supplements compared with no calcium supplements was 0.41 (95% confidence interval 0.29 to 0.60, P<0.001 for trend). Analyses restricted to participants with regular physical exams did not significantly change the association between calcium intake and risk of primary hyperparathyroidism.
conclusionIncreased calcium intake is independently associated with a reduced risk of primary hyperparathyroidism in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.