ArticleSleep & breathing = Schlaf & Atmung2013
Breathing irregularity during wakefulness associates with CPAP acceptance in sleep apnea.
Article in Sleep & breathing = Schlaf & Atmung, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Effects of environment light during sleep on autonomic functions of heart rate and breathing.Sleep & breathing = Schlaf & Atmung · 2014Trial
- Breathing irregularities before sleep onset on polysomnography in patients with heart diseases.Sleep & breathing = Schlaf & Atmung · 2022Article
- C57BL/6J mouse apolipoprotein A2 gene is deterministic for apnea.Respiratory physiology & neurobiology · 2017Article
- Respiratory rate variability in sleeping adults without obstructive sleep apnea.Physiological reports · 2016Article
- Nonrapid Eye Movement-Predominant Obstructive Sleep Apnea: Detection and Mechanism.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015Article
- Brown Norway and Zucker Lean rats demonstrate circadian variation in ventilation and sleep apnea.Sleep · 2014Article
- Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
Abstract
purposeIndividuals have different breathing patterns at rest, during wakefulness, and during sleep, and patients with sleep apnea are no different. The hypothesis for this study was that breathing irregularity during wakefulness associates with CPAP acceptance in obstructive sleep apnea (OSA).
methodsFrom a 2007-2010-database of patients with a diagnostic polysomnography (PSG) and prescribed CPAP (n = 380), retrospectively, 66 patients who quit CPAP treatment at 6 months were identified. Among them, 27 OSA patients quit despite having no side effects for discontinuing CPAP (Group A) and were compared to a matched group (age, body mass index, and apnea-hypopnea index) with good 6-month CPAP adherence (Group B; n = 21). Five minutes of respiratory signal during wakefulness at the initial PSG were extracted from respiratory inductance plethysmography recordings, and measured in a blinded fashion. The coefficients of variation (CV) for the breath-to-breath inspiration time (T i), expiration time (T e), T i + T e (T tot), and relative tidal volume, as well as an independent information theory-based metric of signal pattern variability (mutual information) were compared between groups.
resultsThe CV for tidal volume was significantly greater (p = 0.001), and mutual information was significantly lower (p = 0.041) in Group A as compared to Group B.
conclusionsDifferences in two independent measures of breathing irregularity correlated with CPAP rejection in OSA patients without nasal symptoms or comorbidity. Prospective studies of adherence should examine traits of breathing stability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.