ArticleTransgenic research2013
The polyamine spermine protects Arabidopsis from heat stress-induced damage by increasing expression of heat shock-related genes.
Article in Transgenic research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 146 citations in OpenAlex.
- Dual functions of thermospermine in plant growth and stress responses.Amino acids · 2026Review
- QTL mapping and underlying genes for heat tolerance in grapevine (Rhine Riesling × Cabernet Sauvignon) under field conditions.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- A global assembly of landrace oat (Avena sativa L.) accessions is a discovery resource for adaptive variation, association mapping, and trait deployment.G3 (Bethesda, Md.) · 2025Article
- Phytohormonal homeostasis, chloroplast stability, and heat shock transcription pathways related to the adaptability of creeping bentgrass species to heat stress.Protoplasma · 2025Article
- Chemical application improves stress resilience in plants.Plant molecular biology · 2025Review
- Polyamines Interaction with Gaseous Signaling Molecules for Resilience Against Drought and Heat Stress in Plants.Plants (Basel, Switzerland) · 2025Review
- Appraisal of the Role of Gaseous Signaling Molecules in Thermo-Tolerance Mechanisms in Plants.Plants (Basel, Switzerland) · 2024Review
- Discovering the regulators of heat stress tolerance inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Exogenous spermine alleviates the negative effects of combined salinity and paraquat in tomato plants by decreasing stress-induced oxidative damage.Frontiers in plant science · 2023Article
- Spermidine enhances heat tolerance of rice seeds during mid-filling stage and promote subsequent seed germination.Frontiers in plant science · 2023Article
- Insight into the Molecular Signature of Skeletal Muscle Characterizing Lifelong Football Players.International journal of environmental research and public health · 2022Article
- Transcriptome and Metabolome Analysis Revealed That Exogenous Spermidine-Modulated Flavone Enhances the Heat Tolerance of Lettuce.Antioxidants (Basel, Switzerland) · 2022Article
- The Functional Interplay between Ethylene, Hydrogen Sulfide, and Sulfur in Plant Heat Stress Tolerance.Biomolecules · 2022Review
- Exogenous Putrescine Increases Heat Tolerance in Tomato Seedlings by Regulating Chlorophyll Metabolism and Enhancing Antioxidant Defense Efficiency.Plants (Basel, Switzerland) · 2022Article
- Review
- Role of Promising Secondary Metabolites to Confer Resistance Against Environmental Stresses in Crop Plants: Current Scenario and Future Perspectives.Frontiers in plant science · 2022Review
- Improving water deficit tolerance of Salvia officinalis L. using putrescine.Scientific reports · 2021Article
- Spermidine Induces Expression of Stress Associated Proteins (SAPs) Genes and Protects Rice Seed from Heat Stress-Induced Damage during Grain-Filling.Antioxidants (Basel, Switzerland) · 2021Article
- Gene co-expression network analysis of the heat-responsive core transcriptome identifies hub genes in Brassica rapa.Planta · 2021Article
- AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth.Oncogene · 2021Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is known that the polyamine (PA) biosynthetic pathway is modulated at the transcriptional level during abiotic stresses. Here we studied the expression of PA biosynthetic pathway genes upon exposure to heat shock (HS) in Arabidopsis and showed that the spermine (Spm) synthase gene (SPMS) and S-adenosylmethionine decarboxylase 2 gene are induced at the earliest stage, followed by the induction of the arginine decarboxylase 2 gene. Correspondingly, Spm content increased linearly upon HS, and putrescine (Put) and spermidine (Spd) content also increased but not thermospermine (T-Spm) content. Exogenously applied Spm had a potential to protect Arabidopsis plants from HS-induced damage. Such protection was also observed to the same extent with T-Spm and by Spd to a lesser extent but not by Put. Then we tested whether altered endogenous Spm content affects sensitivity to HS using both transgenic plants overexpressing SPMS and a Spm deficient (spms) mutant plant. The result revealed that the higher the Spm content the higher the thermotolerance. Even in the spms plant, representative genes encoding heat shock proteins (HSPs) and heat shock transcription factors were upregulated upon HS, while the expression of such genes was increased in a positively correlated manner with Spm content. Furthermore four kinds of HSPs (HSP101, HSP90, HSP70 and HSP17.6) were detected proportionally with the levels of their respective transcripts upon HS. We propose that Spm increases the HS response at transcriptional and translational levels and protects host plants from HS-induced damage.
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