ArticleThe journal of headache and pain2012
White matter hyperintensities and self-reported depression in a sample of patients with chronic headache.
Article in The journal of headache and pain, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 18 citations in OpenAlex.
- Profile of Indian Children with Childhood Ataxia and Central Nervous System Hypomyelination/Vanishing White Matter Disease: A Single Center Experience from Southern India.Journal of pediatric genetics · 2021Article
- Cerebral gray matter volume in patients with chronic migraine: correlations with clinical features.The journal of headache and pain · 2017Article
- Behavioral management of headache in children and adolescents.The journal of headache and pain · 2016Review
- The relationship of anxiety, depression and behavioral problems with recurrent headache in late adolescence – a Young-HUNT follow-up study.The journal of headache and pain · 2015Article
- Right fronto-insular white matter tracts link cognitive reserve and pain in migraine patients.The journal of headache and pain · 2015Article
- White matter abnormalities: Insights into the pathophysiology of major affective disorders.World journal of radiology · 2014Article
- Vanishing white matter disease in a spanish population.Journal of central nervous system disease · 2014Review
- Personality traits in chronic daily headache patients with and without psychiatric comorbidity: an observational study in a tertiary care headache center.The journal of headache and pain · 2013Article
- New insights into the cardiovascular risk of migraine and the role of white matter hyperintensities: is gold all that glitters?The journal of headache and pain · 2013Review
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Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
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Abstract
White matter hyperintensities (WMH) have been associated with mood disorders in psychiatric patients. In the present study, we aimed to assess whether WMHs are associated with depressive symptoms and different sensitivity of the behavioral inhibition (BIS), and activation (BAS) systems in patients with chronic headache. Participants were 85 adult outpatients (16 men and 69 women) with a diagnosis of chronic headache. All of the patients underwent brain magnetic resonance imaging (MRI) and were administered the BIS/BAS scales and the Center for Epidemiologic Studies Depression Scale. Above 40 % of patients had periventricular WMHs (PWMHs) and almost 98 % had deep WMHs (DWMHs). Patients with PWMHs reported fewer depressive symptoms than patients without PWMHs. Patients with more severe DWMHs (compared with patients with mild or without DWMH lesions) were older and reported lower scores on the drive dimension of the BIS/BAS scales. In multivariate analyses, patients with PWMHs were 1.06 times more likely to report fewer depressive symptoms than patients without PWMHs. WMH lesions in patients with chronic headache were associated with less depression severity.
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