Evidence map›Paper›PMID 23078583›Full record

Trial reportAlcoholism, clinical and experimental research2013

Validation of the brief Biphasic Alcohol Effects Scale (B-BAES).

Sandra Y Rueger, Andrea C King

Registry-linked trialAbstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Alcoholism, clinical and experimental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04707989 (A Randomized, Placebo Controlled, Study to Evaluate the Tolerance and Safety of a Ketone- Promoting Food Ingredient in Healthy Men and Women), which is not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04707989 nacompletednot on this mapstarted 2020, after this paper: background citation

A Randomized, Placebo Controlled, Study to Evaluate the Tolerance and Safety of a Ketone- Promoting Food Ingredient in Healthy Men and Women

TypeinterventionalSponsorBHB Therapeutics, Ireland LTDRan2020 to 2021Enrolled90ConditionsToleranceArmsKetone- Promoting Food Ingredient #1, Ketone- Promoting Food Ingredient #2, Ketone Free Placebo
3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Trial
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  5. The neurobiological markers of acute alcohol's subjective effects in humans.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
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  10. Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
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  14. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sandra Y RuegerDepartment of Psychology, Wheaton College, Wheaton, Illinois, USA.
Andrea C King

Funding

TRANSLATIONAL RESEARCH UNIVERSITY OF CHICAGO: CLINICAL TRIALSUL1RR024999 · NCRR · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2007 to 2011
$25.3M
Alcohol Stimulation and Sedation in Binge Drinkers - Renewal 01R01AA013746 · NIAAA · UNIVERSITY OF CHICAGO · PI DANIEL J FRIDBERG, ANDREA C KING · 2003 to 2026
$11.6M
NCRR NIH HHS UL1 RR024999NCRR NIH HHS UL1RR024999NIAAA NIH HHS R01 AA013746NIAAA NIH HHS R01-AA013746NIAAA NIH HHS R01-AA013746-S1
6 · The paper itself

Abstract

backgroundThe Biphasic Alcohol Effects Scale (BAES) is a reliable and valid 14-item measure of alcohol's acute stimulant and sedative effects, but its length may preclude use in research paradigms with time constraints on assessment. Here, we report further psychometric support for the 6-item Brief BAES (B-BAES) originally developed by our group in 2009.

methodsTwo studies are included: the first study tested the B-BAES in an independent sample of young adult heavy social drinkers administered 0.8 g/kg alcohol in a laboratory challenge study (N = 104) to confirm the reliability and validity of the 6-item B-BAES. The second study compared the predictive validity of the B-BAES versus the BAES in a separate sample of 104 heavy drinkers who took part in a prospective laboratory alcohol challenge and follow-up study of drinking behaviors.

resultsAn item analysis demonstrated strong support across several intervals on the breath alcohol curve for the same 6 B-BAES items (energized, excited, up, sedated, slow thoughts, sluggish). Confirmatory factor analysis with the B-BAES demonstrated strong support for the same underlying structure as with the full BAES, and tests of internal consistency reliability were very strong to excellent. B-BAES subscale scores correlated highly with corresponding scores of the BAES and predicted binge-drinking frequency during a 2-year follow-up.

conclusionsThese results provide strong psychometric support to confirm use of the B-BAES in studies assessing alcohol's stimulant and sedative properties. The B-BAES may be a useful new tool to enhance the scope of future research assessing alcohol's biphasic effects, particularly in paradigms when time and concise measurement are priorities.

Indexed as

AdultAffectAlcohol DrinkingCohort StudiesDouble-Blind MethodEthanolFemaleFollow-Up StudiesHumansMaleSurveys and QuestionnairesYoung AdultEthanol

Identifiers

PMID23078583
PMCPMC3570663

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.