Evidence map›Paper›PMID 23078580›Full record

ReviewCellular microbiology2013

Chromosome architecture is a key element of bacterial cellular organization.

Jerod L Ptacin, Lucy Shapiro

Abstract readReview
In one paragraph

Review in Cellular microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Coevolution of the Organization and Structure of Prokaryotic Genomes.Cold Spring Harbor perspectives in biology · 2016
    Review
  5. Article
  6. Article
  7. Cell cycle regulation by the bacterial nucleoid.Current opinion in microbiology · 2014
    Review
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jerod L PtacinDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Lucy Shapiro

Funding

REGULATION OF DIFFERENTIATION IN CAULOBACTERR01GM032506 · NIGMS · YESHIVA UNIVERSITY · PI SHAPIRO, LUCILLE · 1985 to 2014
$7.1M
DEVELOPMENT CONTROL OF DNA REPLICATION IN CAULOBACTERR01GM051426 · NIGMS · STANFORD UNIVERSITY · PI SHAPIRO, LUCILLE · 1994 to 2013
$3.8M
3D Chromosome/Replisome Positioning in Bacterial CellsR24GM073011 · NIGMS · STANFORD UNIVERSITY · PI SHAPIRO, LUCILLE · 2005 to 2008
$1.5M
Elucidating the mechanisms of chromosome segregation in C. crescentusF32GM088966 · NIGMS · STANFORD UNIVERSITY · PI PTACIN, JEROD L · 2009 to 2011
$151k
NIGMS NIH HHS F32 GM088966NIGMS NIH HHS F32GM088966-3NIGMS NIH HHS GM073011-04DNIGMS NIH HHS R01 GM032506NIGMS NIH HHS R01 GM051426NIGMS NIH HHS R01 GM51426 R24NIGMS NIH HHS R24 GM073011
6 · The paper itself

Abstract

The bacterial chromosome encodes information at multiple levels. Beyond direct protein coding, genomes encode regulatory information required to orchestrate the proper timing and levels of gene expression and protein synthesis, and contain binding sites and regulatory sequences to co-ordinate the activities of proteins involved in chromosome repair and maintenance. In addition, it is becoming increasingly clear that yet another level of information is encoded by the bacterial chromosome - the three-dimensional packaging of the chromosomal DNA molecule itself and its positioning relative to the cell. This vast structural blueprint of specific positional information is manifested in various ways, directing chromosome compaction, accessibility, attachment to the cell envelope, supercoiling, and general architecture and arrangement of the chromosome relative to the cell body. Recent studies have begun to identify and characterize novel systems that utilize the three-dimensional spatial information encoded by chromosomal architecture to co-ordinate and direct fundamental cellular processes within the cytoplasm, providing large-scale order within the complex clutter of the cytoplasmic compartment.

Indexed as

Bacterial Physiological PhenomenaBacteriaChromosomes, BacterialDNA, BacterialModels, BiologicalDNA, Bacterial

Identifiers

PMID23078580
PMCPMC3660146

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.