ArticlePloS one2012
Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 87 citations in OpenAlex.
- Update on Antisocial Personality Disorder.Current psychiatry reports · 2024Review
- Single-Dose of Testosterone and theFrontiers in behavioral neuroscience · 2020Article
- An integrated analysis of genes and functional pathways for aggression in human and rodent models.Molecular psychiatry · 2019Article
- Association of MAOA genetic variants and resilience with psychosocial stress: A longitudinal study of Syrian refugees.PloS one · 2019Article
- Exploring the genetic correlations of antisocial behaviour and life history traits.BJPsych open · 2018Article
- Sociogenomics in the 21Sociology compass · 2018Article
- Genetic influences on conduct disorder.Neuroscience and biobehavioral reviews · 2018Review
- Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.JAMA psychiatry · 2017Article
- Genetic and Environmental Structure of DSM-IV Criteria for Antisocial Personality Disorder: A Twin Study.Behavior genetics · 2017Article
- Possible association between SIRT1 single nucleotide polymorphisms and predisposition to antisocial personality traits in Chinese adolescents.Scientific reports · 2017Article
- Microsatellite polymorphisms associated with human behavioural and psychological phenotypes including a gene-environment interaction.BMC medical genetics · 2017Article
- Sensation seeking and impulsive traits as personality endophenotypes for antisocial behavior: Evidence from two independent samples.Personality and individual differences · 2017Article
- Genome-wide association study of antisocial personality disorder.Translational psychiatry · 2016Article
- Opportunities and challenges of big data for the social sciences: The case of genomic data.Social science research · 2016Article
- Genome-wide association study of aggressive behaviour in chicken.Scientific reports · 2016Article
- Beyond main effects of gene-sets: harsh parenting moderates the association between a dopamine gene-set and child externalizing behavior.Brain and behavior · 2016Article
- Gene-set and multivariate genome-wide association analysis of oppositional defiant behavior subtypes in attention-deficit/hyperactivity disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2016Article
- Genome-wide analyses of aggressiveness in attention-deficit hyperactivity disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2016Article
- Genetic Correlates of Individual Differences in Sleep Behavior of Free-Living Great Tits (Parus major).G3 (Bethesda, Md.) · 2016Article
- The association between the MAOA 2R genotype and delinquency over time among men: the interactive role of parental closeness and parental incarceration.Criminal justice and behavior · 2016Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Crime poses a major burden for society. The heterogeneous nature of criminal behavior makes it difficult to unravel its causes. Relatively little research has been conducted on the genetic influences of criminal behavior. The few twin and adoption studies that have been undertaken suggest that about half of the variance in antisocial behavior can be explained by genetic factors. In order to identify the specific common genetic variants underlying this behavior, we conduct the first genome-wide association study (GWAS) on adult antisocial behavior. Our sample comprised a community sample of 4816 individuals who had completed a self-report questionnaire. No genetic polymorphisms reached genome-wide significance for association with adult antisocial behavior. In addition, none of the traditional candidate genes can be confirmed in our study. While not genome-wide significant, the gene with the strongest association (p-value = 8.7×10(-5)) was DYRK1A, a gene previously related to abnormal brain development and mental retardation. Future studies should use larger, more homogeneous samples to disentangle the etiology of antisocial behavior. Biosocial criminological research allows a more empirically grounded understanding of criminal behavior, which could ultimately inform and improve current treatment strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.