ReviewCurrent allergy and asthma reports2013
Overview of component resolved diagnostics.
Review in Current allergy and asthma reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 106 citations in OpenAlex.
- Quantum Dot Bioconjugates Enable Order(s)-of-Magnitude Enhancement of Immunoglobulin E Detection Sensitivity.ACS omega · 2026Article
- Processionary Moth Exposure in Europe: Toxic-Irritant and Immunoglobulin E-Mediated Endotypes, Diagnosis and Management.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Review
- In vitro IgE diagnostics in inhalant allergy: Plant and mold allergens.Allergologie select · 2026Review
- Concordance between crude extract and component allergens in a multiple allergen simultaneous test: a large-scale retrospective analysis.British journal of biomedical science · 2026Article
- Characterization of the clinical relevance and hypoallergenic peptides of the newly evidenced major allergen Hum j 1.Frontiers in immunology · 2025Article
- Tree Nut Allergy in Children-What Do We Know? -A Review.Nutrients · 2024Review
- Diagnostic Decision Point for IgE-Mediated Wheat Allergy in Children.Allergy, asthma & immunology research · 2024Article
- Identifying patients at risk of anaphylaxis.The World Allergy Organization journal · 2024Review
- Recurrent Food-Induced Anaphylaxis in a Child: A Rare Case Report.Turkish archives of pediatrics · 2024Article
- Occupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI).Allergologie select · 2024Article
- Fruitful or unfruitful: strawberry and tomato specific immunoglobulin E testing at a tertiary pediatric center.Frontiers in allergy · 2023Article
- Prevalence of sensitization to molecular food allergens in Europe: A systematic review.Clinical and translational allergy · 2022Review
- Asthma and Allergy: Unravelling a Tangled Relationship with a Focus on New Biomarkers and Treatment.International journal of molecular sciences · 2022Review
- Combining Anti-IgE Monoclonal Antibodies and Oral Immunotherapy for the Treatment of Food Allergy.Clinical reviews in allergy & immunology · 2022Review
- Update on Type-1 Allergy Diagnostics.Handbook of experimental pharmacology · 2022Article
- Component resolved diagnosis and risk assessment in food allergy.Acta bio-medica : Atenei Parmensis · 2021Article
- Article
- Sensitization profile to sawtooth oak component allergens and their clinical implications.Journal of clinical laboratory analysis · 2021Article
- The use of microarray and other multiplex technologies in the diagnosis of allergy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021Review
- Turkish Guideline for Diagnosis and Treatment of Allergic Rhinitis (ART).Turkish archives of otorhinolaryngology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Component-resolved diagnostics (CRD) utilize purified native or recombinant allergens to detect IgE sensitivity to individual allergen molecules and have become of growing importance in clinical investigation of IgE-mediated allergies. This overview updates current developments of CRD, including multiarray test systems. Cross-reactions between allergens of known allergen families (i.e. to Bet v 1 homologues) are emphasised. In pollinosis as well as in allergy to hymenoptera venoms or to food, CRD allows to some extent discrimination between clinically significant and irrelevant sIgE results and the establishing of sensitisation patterns with particular prognostic outcomes (i.e. sensitisations to storage proteins which correlate with clinically severe reactions in peanut allergy). Further promising improvements in diagnostics are expected from additional, not yet commercially available, recombinant allergen diagnostics identifying particular molecules of risk. Overall, CRD may decrease the need for provocation testing and may also improve the specificity of allergen-specific immunotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.