Evidence map›Paper›PMID 23076284›Full record

ArticleVirulence2012

Detection of Streptococcus pyogenes virulence factors by multiplex PCR.

Anna L Borek, Katarzyna Obszańska, Waleria Hryniewicz, Izabela Sitkiewicz

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Biological Characterization and Inhibition ofMolecules (Basel, Switzerland) · 2019
    Article
  6. Article
  7. AnFrontiers in microbiology · 2017
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna L BorekDepartment of Epidemiology and Clinical Microbiology, National Medicines Institute, Warszawa, Poland.
Katarzyna Obszańska
Waleria Hryniewicz
Izabela Sitkiewicz
Narodowy Instytut Leków · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcus pyogenes (GAS) is a human pathogen that causes multiple infections worldwide. The pathogenic properties of GAS strains are often linked to the production of virulence factors such as toxins, proteases or DNases. Detection of virulence factors produced by GAS strains can be used to either determine pathogenic potential of the strain or as a rapid screening and typing method. We recently developed a method to detect simultaneously 20 GAS virulence factors (spd3, sdc, sdaB, sdaD, speB, spyCEP, scpA, mac, sic, speL, K, M, C, I, A, H, G, J, smeZ and ssa) in four low volume multiplex PCR reactions (Borek et al., 2011) and below we present a detailed protocol describing the method.

Indexed as

Bacterial ProteinsMultiplex Polymerase Chain ReactionStreptococcal InfectionsStreptococcus pyogenesVirulence FactorsBacterial ProteinsVirulence Factors

Identifiers

PMID23076284
PMCPMC3524156
OpenAlexW2002694072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.