ReviewNature reviews. Genetics2012
Next-generation sequencing in the clinic: are we ready?
Review in Nature reviews. Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed.
- Personalized genomic disease risk of volunteers.Proceedings of the National Academy of Sciences of the United States of America · 2013Trial
- SARS-CoV-2 Illumina GeNome Assembly Line (SIGNAL), a Snakemate workflow for rapid and bulk analysis of Illumina sequencing of SARS-CoV-2 genomes.NAR genomics and bioinformatics · 2024Article
- Toward a More Just System of Care in Molecular Pathology.The Milbank quarterly · 2022Article
- Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement From the American Heart Association.Circulation · 2022Review
- Next-Generation Sequencing Technologies and Neurogenetic Diseases.Life (Basel, Switzerland) · 2021Review
- RNA sequencing reveals the expression profiles of circRNA and identifies a four-circRNA signature acts as a prognostic marker in esophageal squamous cell carcinoma.Cancer cell international · 2021Article
- Selecting Classification Methods for Small Samples of Next-Generation Sequencing Data.Frontiers in genetics · 2021Article
- Adaptive response of resistant cancer cells to chemotherapy.Cancer biology & medicine · 2020Review
- Portable Rabies Virus Sequencing in Canine Rabies Endemic Countries Using the Oxford Nanopore MinION.Viruses · 2020Article
- Laboratory Approach to Hemolytic Anemia.Indian journal of pediatrics · 2020Review
- Prognostic value of a five-lncRNA signature in esophageal squamous cell carcinoma.Cancer cell international · 2020Article
- RegulationSpotter: annotation and interpretation of extratranscriptic DNA variants.Nucleic acids research · 2019Article
- Ethics in genetic counselling.Journal of community genetics · 2019Review
- Impact of Receiving Secondary Results from Genomic Research: A 12-Month Longitudinal Study.Journal of genetic counseling · 2018Article
- Clinical providers' experiences with returning results from genomic sequencing: an interview study.BMC medical genomics · 2018Article
- Protein-coding genes combined with long noncoding RNA as a novel transcriptome molecular staging model to predict the survival of patients with esophageal squamous cell carcinoma.Cancer communications (London, England) · 2018Article
- A systematic review on the genetics of male infertility in the era of next-generation sequencing.Arab journal of urology · 2018Article
- Case series of multiple primary cancers in single individuals: diagnostic and therapeutic dilemmas.Journal of community hospital internal medicine perspectives · 2017Article
- Unsolicited findings of next-generation sequencing for tumor analysis within a Dutch consortium: clinical daily practice reconsidered.European journal of human genetics : EJHG · 2016Article
- Parents' Experience with Pediatric Microarray: Transferrable Lessons in the Era of Genomic Counseling.Journal of genetic counseling · 2016Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We are entering an era in which the cost of clinical whole-genome and targeted sequencing tests is no longer prohibitive to their application. However, currently the infrastructure is not in place to support both the patient and the physicians that encounter the resultant data. Here, we ask five experts to give their opinions on whether clinical data should be treated differently from other medical data, given the potential use of these tests, and on the areas that must be developed to improve patient outcome.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.