Evidence map›Paper›PMID 23074992›Full record

ArticleAccountability in research2012

Reflexive research ethics in fetal tissue xenotransplantation research.

Bindu Panikkar, Natasha Smith, Phil Brown

Abstract read
In one paragraph

Article in Accountability in research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Social Science-Environmental Health Collaborations: An Exciting New Direction.New solutions : a journal of environmental and occupational health policy : NS · 2016
    Article
  5. Article
  6. Xenotransplantation models to study the effects of toxicants on human fetal tissues.Birth defects research. Part B, Developmental and reproductive toxicology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bindu PanikkarSocial Science Environmental Health Research Institute, Northeastern University, Boston, Massachusetts 02115, USA. bpanikkar@hotmail.com
Natasha Smith
Phil Brown
Northeastern University · USUniversity of Wisconsin–Madison · US

Funding

Xenotransplant CoreP20ES018169 · NIEHS · BROWN UNIVERSITY · PI GRUPPUSO, PHILIP A. · 2010 to 2012
$985k
NIEHS NIH HHS 1P20ES018169NIEHS NIH HHS P20 ES018169
6 · The paper itself

Abstract

For biomedical research in which the only involvement of the human subject is the provision of tissue or organ samples, a blanket consent, i.e., consent to use the tissue for anything researchers wish to do, is considered by many to be adequate for legal and Institutional Review Board (IRB) requirements. Alternatively, a detailed informed consent provides patients or study participants with more thorough information about the research topic. We document here the beliefs and opinions of the research staff on informed consent and the discussion-based reflexive research ethics process that we employed in our fetal tissue xenotransplantion research on the impact of environmental exposures on fetal development. Reflexive research ethics entails the continued adjustment of research practice according to relational and reflexive understandings of what might be beneficent or harmful. Such reflexivity is not solely an individual endeavor, but rather a collective relationship between all actors in the research process.

Indexed as

Ethics, ResearchTransplantation, HeterologousAnimalsFetal Tissue TransplantationHumansInformed Consent

Identifiers

PMID23074992
PMCPMC3689847
OpenAlexW2066931136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.