Evidence map›Paper›PMID 23074355›Full record

ArticleMathematical population studies2012

Asymptotic behavior of cell populations described by two-type reducible age-dependent branching processes with non-homogeneous immigration().

Ollivier Hyrien, Nikolay M Yanev

Abstract read
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In one paragraph

Article in Mathematical population studies, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ollivier HyrienDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, New York, U.S.A.
Nikolay M Yanev

Funding

Modeling B Cell Vaccine Responses in Transplant RecipientsR01AI069351 · NIAID · UNIVERSITY OF ROCHESTER · PI HYRIEN, OLLIVIER, ZAND, MARTIN S · 2007 to 2016
$3.7M
STOCHASTIC MODELING OF MULTI TYPE CELL SYSTEMSR01NS039511 · NINDS · UNIVERSITY OF UTAH · PI HYRIEN, OLLIVIER · 2001 to 2011
$3.2M
Modeling Immune Desensitization in Renal TransplantationR01AI098112 · NIAID · UNIVERSITY OF ROCHESTER · PI ZAND, MARTIN S · 2012 to 2016
$1.9M
Statistical Inference on Chemotherapy Effects from Flow Cytometry DataR01CA134839 · NCI · UNIVERSITY OF ROCHESTER · PI HYRIEN, OLLIVIER · 2008 to 2012
$1.2M
NCI NIH HHS R01 CA134839NIAID NIH HHS R01 AI069351NIAID NIH HHS R01 AI098112NINDS NIH HHS R01 NS039511
6 · The paper itself

Abstract

Stem and precursor cells play a critical role in tissue development, maintenance, and repair throughout the life. Often, experimental limitations prevent direct observation of the stem cell compartment, thereby posing substantial challenges to the analysis of such cellular systems. Two-type age-dependent branching processes with immigration are proposed to model populations of progenitor cells and their differentiated progenies. Immigration of cells into the pool of progenitor cells is formulated as a non-homogeneous Poisson process. The asymptotic behavior of the process is governed by the largest of two Malthusian parameters associated with embedded Bellman-Harris processes. Asymptotic approximations to the expectations of the total cell counts are improved by Markov compensators.

Identifiers

PMID23074355
PMCPMC3468160

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.