ReviewAngewandte Chemie (International ed. in English)2012
A continuum of progress: applications of N-hetereocyclic carbene catalysis in total synthesis.
Review in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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Who cites it
64 citing papers in PubMed.
- Review
- Cooperative NHC and Photoredox Dual Catalysis for the Construction of Carbonyl Compounds.ACS omega · 2026Review
- Catalytic Enantioselective Methods for Synthesis of 1,2-Amino Tertiary Alcohols and Their Analogues.Chemical reviews · 2025Review
- Umpolung Activation of Bicyclobutanes via N-Heterocyclic Carbene Catalysis.Angewandte Chemie (International ed. in English) · 2025Article
- N-heterocyclic carbene-catalyzed atroposelective synthesis of N-Aryl phthalimides and maleimides via activation of carboxylic acids.Nature communications · 2024Article
- Redox Active N-Heterocyclic Carbenes in Oxidative NHC Catalysis.Organic letters · 2024Article
- Synthesis of N-, O-, and S-heterocycles from aryl/alkyl alkynyl aldehydes.RSC advances · 2023Review
- Article
- A (TD-)DFT study on photo-NHC catalysis: photoenolization/Diels-Alder reaction of acid fluorides catalyzed byChemical science · 2023Article
- Oxidative N-Heterocyclic Carbene Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Review
- Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists.Molecules (Basel, Switzerland) · 2022Review
- An umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition of aryl aldehydes and nitriles: a facile access to 2,4,5-trisubstituted oxazoles.Chemical science · 2022Article
- Synthesis of Highly Congested Tertiary Alcohols via the [3,3] Radical Deconstruction of Breslow Intermediates.Organic letters · 2022Article
- N-Heterocyclic carbene (NHC)-catalyzed oxidation of unactivated aldimines to amidesRSC advances · 2022Article
- Synthesis and investigation of antiproliferative activity of Ru-NHC complexes against C6 and HeLa cancer cells.Turkish journal of chemistry · 2022Article
- Halogen-containing heteroaromatic carbenes of the 1,2,4-triazole series and their transformations.RSC advances · 2021Article
- Tale of the Breslow intermediate, a central player in N-heterocyclic carbene organocatalysis: then and now.Chemical science · 2021Review
- Direct α-Acylation of Alkenes via N-Heterocyclic Carbene, Sulfinate, and Photoredox Cooperative Triple Catalysis.Journal of the American Chemical Society · 2021Article
- NHC-catalyzed covalent activation of heteroatoms for enantioselective reactions.Chemical science · 2021Review
- N-Heterocyclic carbene-catalyzed enantioselective hetero-[10 + 2] annulation.Communications chemistry · 2020Article
4 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
N-Heterocyclic carbene (NHC) catalyzed transformations have emerged as powerful tactics for the construction of complex molecules. Since Stetter's report in 1975 of the total synthesis of cis-jasmon and dihydrojasmon by using carbene catalysis, the use of NHCs in total synthesis has grown rapidly, particularly over the last decade. This renaissance is undoubtedly due to the recent developments in NHC-catalyzed reactions, including new benzoin, Stetter, homoenolate, and aroylation processes. These transformations employ typical as well as Umpolung types of bond disconnections and have served as the key step in several new total syntheses. This Minireview highlights these reports and captures the excitement and emerging synthetic utility of carbene catalysis in total synthesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.