Evidence map›Paper›PMID 23073954›Full record

ArticleJAMA2012

Strategies to help a smoker who is struggling to quit.

Nancy A Rigotti

Abstract readCase ReportsClinical Conference
In one paragraph

Article in JAMA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Tobacco cessation: screening and interventions.Korean journal of family medicine · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Tobacco Use and Treatment of Tobacco Dependence Among People With Human Immunodeficiency Virus: A Practical Guide for Clinicians.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Immunological and toxicological risk assessment of e-cigarettes.European respiratory review : an official journal of the European Respiratory Society · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Nancy A RigottiTobacco Research and Treatment Center and General Medicine Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA. nrigotti@partners.org

Funding

Smoking Cessation Interventions for Health Care SettingsK24HL004440 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI RIGOTTI, NANCY A · 2000 to 2009
$1.5M
NHLBI NIH HHS 5K24HL4440-10NHLBI NIH HHS K24 HL004440
6 · The paper itself

Abstract

Tobacco use is the leading preventable cause of death worldwide. Stopping tobacco use benefits virtually every smoker. Most of the 19% of US residents who smoke want to quit and have tried to do so. Most individual quit attempts fail, but two-thirds of smokers use no treatment when trying to quit. Treating tobacco dependence is one of the most cost-effective actions in health care. With a brief intervention, physicians can prompt smokers to attempt to quit and connect them to evidence-based treatment that includes pharmacotherapy and behavioral support (ie, counseling). Physicians can link smokers to effective counseling support offered by a free national network of telephone quit lines. Smokers who use nicotine replacement therapy (NRT), bupropion, or varenicline when trying to quit double their odds of success. The most effective way to use NRT is to combine the long-acting nicotine patch with a shorter-acting product (lozenge, gum, inhaler, or nasal spray) and extend treatment beyond 12 weeks. Observational studies have not confirmed case reports of behavior changes associated with varenicline and bupropion, and these drugs' benefits outweigh potential risks. A chronic disease management model is effective for treating tobacco dependence, which deserves as high a priority in health care systems as treating other chronic diseases like diabetes and hypertension.

Indexed as

CounselingTobacco Use Cessation DevicesBehavior TherapyBenzazepinesBupropionChronic DiseaseDisease ManagementDopamine Uptake InhibitorsHotlinesHumansMaleMiddle AgedNicotinic AgonistsPhysician-Patient RelationsPhysician's RoleQuinoxalinesBenzazepinesBupropionDopamine Uptake InhibitorsNicotinic AgonistsQuinoxalinesVarenicline

Identifiers

PMID23073954
PMCPMC4562427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.