ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2012
Imaging atherosclerosis with hybrid [18F]fluorodeoxyglucose positron emission tomography/computed tomography imaging: what Leonardo da Vinci could not see.
Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01456403 (Histological Validation Of Carotid Plaque Composition In Preoperative Imaging Of Patients Scheduled For Carotid Endarterectomy), which is not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Histological Validation Of Carotid Plaque Composition In Preoperative Imaging Of Patients Scheduled For Carotid Endarterectomy
Who cites it
23 citing papers in PubMed, 59 citations in OpenAlex.
- Preclinical evaluation of high-resolution CT,European journal of nuclear medicine and molecular imaging · 2025Article
- Does Systemic Anti-Psoriatic Treatment Impact the Risk of Cardiovascular Disease? A Review Over Cardiovascular Imaging Studies.Dermatology and therapy · 2024Review
- Sleep apnea and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA): leveraging state-of-the-art vascular imaging.The international journal of cardiovascular imaging · 2023Article
- Iterative reconstruction incorporating background correction improves quantification of [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Detection of pulmonary artery atherosclerosis by FDG-PET/CT: a new observation.American journal of nuclear medicine and molecular imaging · 2020Article
- Review
- Lesion contrast recovery for partial-volume averaging: Quantitative correction or qualitative enhancement?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Review
- Radiopharmaceutical tracers for cardiac imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Effect of Pioglitazone in Combination with Moderate Dose Statin on Atherosclerotic Inflammation: Randomized Controlled Clinical Trial Using Serial FDG-PET/CT.Korean circulation journal · 2018Article
- Correlation of FDG PET/CT Findings with Long-Term Growth and Clinical Course of Abdominal Aortic Aneurysm.Nuclear medicine and molecular imaging · 2018Article
- Imaging Subclinical Atherosclerosis: Where Do We Stand?Current cardiology reviews · 2017Review
- Molecular magnetic resonance imaging of atherosclerotic vessel wall disease.European radiology · 2016Review
- Management of Patients with an Asymptomatic Carotid Stenosis--Medical Management, Endovascular Treatment, or Carotid Endarterectomy?Current neurology and neuroscience reports · 2016Review
- Natural history of atherosclerotic disease progression as assessed by (18)F-FDG PET/CT.The international journal of cardiovascular imaging · 2016Article
- Recent advances in pathogenesis, assessment, and treatment of atherosclerosis.F1000Research · 2016Review
- Aortic ¹⁸F-FDG uptake in patients suffering from granulomatosis with polyangiitis.European journal of nuclear medicine and molecular imaging · 2015Article
- Imaging VEGF receptor expression to identify accelerated atherosclerosis.EJNMMI research · 2014Article
- Carotid Artery FDG Uptake May Serve as a Biomarker for Cardiovascular Risk Stratification in Asymptomatic Adults.Nuclear medicine and molecular imaging · 2014Article
- PET imaging of inflammation in atherosclerosis.Nature reviews. Cardiology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Prodigious efforts and landmark discoveries have led toward significant advances in our understanding of atherosclerosis. Despite significant efforts, atherosclerosis continues globally to be a leading cause of mortality and reduced quality of life. With surges in the prevalence of obesity and diabetes, atherosclerosis is expected to have an even more pronounced impact upon the global burden of disease. It is imperative to develop strategies for the early detection of disease. Positron emission tomography (PET) imaging utilizing [(18)F]fluorodeoxyglucose (FDG) may provide a non-invasive means of characterizing inflammatory activity within atherosclerotic plaque, thus serving as a surrogate biomarker for detecting vulnerable plaque. The aim of this review is to explore the rationale for performing FDG imaging, provide an overview into the mechanism of action, and summarize findings from the early application of FDG PET imaging in the clinical setting to evaluate vascular disease. Alternative imaging biomarkers and approaches are briefly discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.