ArticlePloS one2012
Association mapping and haplotype analysis of a 3.1-Mb genomic region involved in Fusarium head blight resistance on wheat chromosome 3BS.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A chickpea MAGIC population to dissect the genetics of complex traits.The plant genome · 2025Article
- Identification of environment-insensitive genes for oil content by combination of transcriptome and genome-wide association analysis in rapeseed.Biotechnology for biofuels and bioproducts · 2024Article
- Breeding effects on durum wheat traits detected using GWAS and haplotype block analysis.Frontiers in plant science · 2023Article
- Apoptotic-like PCD inducing HRC gene when silenced enhances multiple disease resistance in plants.Scientific reports · 2022Article
- Evaluation of Fusarium Head Blight Resistance Effects by Haplotype-Based Genome-Wide Association Study in Winter Wheat Lines Derived by Marker Backcrossing Approach.International journal of molecular sciences · 2022Article
- Genome-wide association study in hexaploid wheat identifies novel genomic regions associated with resistance to root lesion nematode (Pratylenchus thornei).Scientific reports · 2021Article
- Methodical Considerations and Resistance Evaluation againstMicroorganisms · 2020Article
- WFhb1-1 plays an important role in resistance against Fusarium head blight in wheat.Scientific reports · 2020Article
- Discovering new alleles for yellow spot resistance in the Vavilov wheat collection.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Development and validation of diagnostic markers for Fhb1 region, a major QTL for Fusarium head blight resistance in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- High Levels of Variation Within Gene Sequences ofFrontiers in plant science · 2018Article
- Unlocking new alleles for leaf rust resistance in the Vavilov wheat collection.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Article
- Wheat Fhb1 encodes a chimeric lectin with agglutinin domains and a pore-forming toxin-like domain conferring resistance to Fusarium head blight.Nature genetics · 2016Article
- Suppressed recombination and unique candidate genes in the divergent haplotype encoding Fhb1, a major Fusarium head blight resistance locus in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Effective marker alleles associated with type 2 resistance to Fusarium head blight infection in fields.Breeding science · 2016Article
- A genome-wide association study of resistance to stripe rust (Puccinia striiformis f. sp. tritici) in a worldwide collection of hexaploid spring wheat (Triticum aestivum L.).G3 (Bethesda, Md.) · 2015Article
- Use of single nucleotide polymorphisms and haplotypes to identify genomic regions associated with protein content and water-soluble protein content in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- Article
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6 authors.
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Abstract
A previous study provided an in-depth understanding of molecular population genetics of European and Asian wheat gene pools using a sequenced 3.1-Mb contig (ctg954) on chromosome 3BS. This region is believed to carry the Fhb1 gene for response to Fusarium head blight. In this study, 266 wheat accessions were evaluated in three environments for Type II FHB response based on the single floret inoculation method. Hierarchical clustering (UPGMA) based on a Manhattan dissimilarity matrix divided the accessions into eight groups according to five FHB-related traits which have a high correlation between them; Group VIII comprised six accessions with FHB response levels similar to variety Sumai 3. Based on the compressed mixed linear model (MLM), association analysis between five FHB-related traits and 42 molecular markers along the 3.1-Mb region revealed 12 significant association signals at a threshold of P<0.05. The highest proportion of phenotypic variation (6.2%) in number of diseased spikelets (NDS) occurred at locus cfb6059, and the physical distance was about 2.9 Kb between umn10 and this marker. Haplotype block (HapB) analysis using a sliding window LD of 5 markers, detected six HapBs in the 3.1-Mb region at r(2)>0.1 and P<0.001 between random closely linked markers. F-tests among Haps with frequencies >0.05 within each HapB at r(2)>0.1 and P<0.001 showed significant differences between the Hap carried by FHB resistant resources, such as Sumai 3 and Wangshuibai, and susceptible genotypes in HapB3 and HapB6. These results suggest that Fhb1 is located within HapB6, with the possibility that another gene is located at or near HapB3. SSR markers and Haps detected in this study will be helpful in further understanding the genetic basis of FHB resistance, and provide useful information for marker-assisted selection of Fhb1 in wheat breeding.
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