ArticleCase reports in ophthalmology2012
Management of Stage IV Macular Holes: When Standard Surgery Fails.
Article in Case reports in ophthalmology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Optimal approaches for managing recurrent macular holes: a comprehensive systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Temporal Arcuate Relaxing Retinotomy for Persistent Full-Thickness Macular Holes: Anatomical and Functional Assessment.Journal of clinical medicine · 2026Article
- Comparison of the therapeutic effects of lens capsular flap transplantation and autologous retinal transplantation in the management of refractory macular holes.International ophthalmology · 2024Article
- Autologous internal limiting membrane transplantation achieves anatomic closure and functional improvement in the treatment of large, persistent macular holes.International journal of retina and vitreous · 2024Article
- Macular Hole Surgery as a Historical Perspective.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- A three-step approach to close refractory persistent macular holes: a releasing-closing-tapping approach.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Relaxing Retinotomy in Recurrent and Refractory Full-Thickness Macular Holes: The State of the Art.Life (Basel, Switzerland) · 2023Review
- Commentary: To evaluate the functional and anatomical outcomes for autologous retinal autograft with Finesse™ Flex Loop for failed macular holes.Indian journal of ophthalmology · 2022Article
- Refractory full thickness macular hole: current surgical management.Eye (London, England) · 2022Review
- Surgical Management of Recurrent and Persistent Macular Holes: A Practical Approach.Ophthalmology and therapy · 2021Article
- Viscostretch: A Novel Surgical Technique for Refractory Macular Holes.Journal of vitreoretinal diseases · 2020Article
- MANAGEMENT OF LARGE OR RECURRENT MACULAR HOLES.Current ophthalmology reports · 2020Article
- Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
- A Review of Surgical Outcomes and Advances for Macular Holes.Journal of ophthalmology · 2018Review
- Anatomical and Functional Outcomes of Relaxing Parafoveal Nasal Retinotomy for Refractory Macular Hole Repair.Journal of vitreoretinal diseasesArticle
- Current management strategies for atypical macular holes.Taiwan journal of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report the surgical outcomes of reoperation of unclosed macular holes after initial vitrectomy with internal limiting membrane peeling. PROCEDURES: Seven eyes of 7 patients were submitted to a second procedure in which five radial retinal incisions were made, as deep as the retinal pigment epithelium, beginning one hole diameter away from its borders and extending centripetally until the hole's margins, avoiding the papilomacular bundle. Gas tamponade was performed and face-down positioning was recommended.
resultsAnatomical closure was achieved in all cases with the second procedure. Functional success was achieved in every patient; there was no loss of best corrected visual acuity (BCVA) lines. Mean line score gain was 5.6 lines (range 1-9 lines), with a mean final BCVA of 0.42 (range 0.05-0.5).
conclusionsPerifoveal relaxing incisions in stage IV macular holes that remained unclosed after internal limiting membrane peeling vitrectomy seem to have a positive effect on MH closure rates. Larger case series and an extended follow-up period are necessary in order to assess the efficacy and safety profile of this so far promising technique.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.