Saving lives by training innate immunity with bacille Calmette-Guerin vaccine.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Who cites it

31 citing papers in PubMed.

1. BCG vaccination at birth and early childhood hospitalisation: a randomised clinical multicentre trial.Archives of disease in childhood · 2017
   Trial
2. Metabolic support of trained immune responses in myeloid cells.eLife · 2026
   Review
3. Tissue context as a determinant of trained innate immunity: a conserved molecular toolkit with divergent functional outputs.Journal of leukocyte biology · 2026
   Review
4. Trained immunity in cancer and autoimmunity: a double-edged sword in immune memory reprogramming.Frontiers in immunology · 2026
   Review
5. Nucleotide-Binding Oligomerization Domain 2 in Signaling, Immunity, and Mycobacterial Infection.Immunity, inflammation and disease · 2025
   Review
6. Harnessing Actinobacteria secondary metabolites for tuberculosis drug discovery: Historical trends, current status and future outlooks.Natural products and bioprospecting · 2025
   Review
7. Reversing inflammatory diseases via trained immunity: mechanisms, challenges, and prospects.Frontiers in immunology · 2025
   Review
8. Frontiers in immunology · 2025
   Article
9. Host Genetic Background Influences BCG-Induced Antibodies Cross-Reactive to SARS-CoV-2 Spike Protein.Vaccines · 2024
   Article
10. The causes and consequences of trained immunity in myeloid cells.Frontiers in immunology · 2024
    Review
11. BCG activation of trained immunity is associated with induction of cross reactive COVID-19 antibodies in a BCG vaccinated population.PloS one · 2024
    Article
12. Trained Immunity, BCG and SARS-CoV-2 General Outline and Possible Management in COVID-19.International journal of molecular sciences · 2023
    Review
13. Trained immunity: A "new" weapon in the fight against infectious diseases.Frontiers in immunology · 2023
    Review
14. It Takes a Village: The Multifaceted Immune Response toFrontiers in immunology · 2022
    Review
15. A century of BCG vaccination: Immune mechanisms, animal models, non-traditional routes and implications for COVID-19.Frontiers in immunology · 2022
    Review
16. Safety and Seroconversion of Immunotherapies against SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis of Clinical Trials.Pathogens (Basel, Switzerland) · 2021
    Review
17. Rationale for Randomized Clinical Trials Investigating the Potential of BCG Vaccination in Preventing COVID-19 Infection.Bladder cancer (Amsterdam, Netherlands) · 2021
    Review
18. Vaccine-Induced Immunological Memory in Invasive Fungal Infections - A Dream so Close yet so Far.Frontiers in immunology · 2021
    Review
19. NOD2-dependent BCG-induced trained immunity: A way to regulate innate responses to SARS-CoV2?International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
20. Proposing BCG Vaccination forMicroorganisms · 2020
    Review

Corrections and comments

• Comment on
  Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes.2012

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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