ArticleEuropean cells & materials2012
Biodegradable photo-crosslinked alginate nanofibre scaffolds with tuneable physical properties, cell adhesivity and growth factor release.
Article in European cells & materials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Transformation of the Biological Paradigm in Bone Regeneration: An Integrative Review.Journal of developmental biology · 2026Review
- Article
- Alginate-Based Electrospun Nanofibers and the Enabled Drug Controlled Release Profiles: A Review.Biomolecules · 2024Review
- Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing.Polymers · 2024Article
- Preparation and characterization ofFrontiers in pharmacology · 2024Article
- Article
- Alginate-Based Bio-Composites and Their Potential Applications.Journal of functional biomaterials · 2022Review
- Electrospinning Drug-Loaded Alginate-Based Nanofibers towards Developing a Drug Release Rate Catalog.Polymers · 2022Article
- Current Understanding of the Applications of Photocrosslinked Hydrogels in Biomedical Engineering.Gels (Basel, Switzerland) · 2022Review
- In Vivo Evaluation of Gamma-Irradiated and Heparin-Immobilized Small-Diameter Polycaprolactone Vascular Grafts with VEGF in Aged Rats.Polymers · 2022Article
- Current Trends in Advanced Alginate-Based Wound Dressings for Chronic Wounds.Journal of personalized medicine · 2021Review
- Electrospun Alginate Nanofibers Toward Various Applications: A Review.Materials (Basel, Switzerland) · 2020Review
- Materials-Directed Differentiation of Mesenchymal Stem Cells for Tissue Engineering and Regeneration.ACS biomaterials science & engineering · 2018Article
- Keratin hydrogel carrier system for simultaneous delivery of exogenous growth factors and muscle progenitor cells.Journal of biomedical materials research. Part B, Applied biomaterials · 2016Article
- Stem Cells in Skin Wound Healing: Are We There Yet?Advances in wound care · 2016Review
- Production of new 3D scaffolds for bone tissue regeneration by rapid prototyping.Journal of materials science. Materials in medicine · 2016Article
- Marine polysaccharides from algae with potential biomedical applications.Marine drugs · 2015Review
- The incorporation of bFGF mediated by heparin into PCL/gelatin composite fiber meshes for guided bone regeneration.Drug delivery and translational research · 2015Article
- Bioactive factor delivery strategies from engineered polymer hydrogels for therapeutic medicine.Progress in polymer science · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Nanofibrous scaffolds are of interest in tissue engineering due to their high surface area to volume ratio, interconnected pores, and architectural similarity to the native extracellular matrix. Our laboratory recently developed a biodegradable, photo-crosslinkable alginate biopolymer. Here, we show the capacity of the material to be electrospun into a nanofibrous matrix, and the ability to enhance cell adhesion and proliferation on these matrices by covalent modification with cell adhesion peptides. Additionally, the potential of covalently incorporating heparin into the hydrogels during the photopolymerisation process to sustain the release of a heparin binding growth factor via affinity interactions was demonstrated. Electrospun photo-crosslinkable alginate nanofibrous scaffolds endowed with cell adhesion ligands and controlled delivery of growth factors may allow for improved regulation of cell behaviour for regenerative medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.