Evidence map›Paper›PMID 23070788›Full record

ArticleEndocrine pathology2012

Expression of stromal cell-derived factor 1 and CXCR7 in papillary thyroid carcinoma.

Zhen Liu, Da-Xin Sun, Xu-Yong Teng, Wei-Xue Xu, Xiang-Peng Meng, Bao-Sheng Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Endocrine pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. A new molecular subclassification andFrontiers in pharmacology · 2023
    Article
  4. Article
  5. Sex Bias in Differentiated Thyroid Cancer.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Review
  8. Immune Landscape of Thyroid Cancers: New Insights.Frontiers in endocrinology · 2020
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Immune regulation by atypical chemokine receptors.Nature reviews. Immunology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhen LiuDepartment of General Surgery, Shengjing Hospital, China Medical University, Shenyang, China. liuz@sj-hospital.org
Da-Xin Sun
Xu-Yong Teng
Wei-Xue Xu
Xiang-Peng Meng
Bao-Sheng Wang
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stromal cell-derived factor 1 (SDF-1) is a chemokine that is expressed in some cancer cells and is involved in tumor cell migration and metastasis. CXCR7, a novel receptor for SDF-1, has been identified recently. Researches demonstrated that interaction between SDF-1 and CXCR7 could play an important role in cancer progression. In this study, we aimed to investigate the expressions of SDF-1 and CXCR7 and the relationship between their expressions and clinicopathological characteristics in papillary thyroid carcinoma (PTC). Expressions of SDF-1 and CXCR7 in 33 cases of thyroid benign lesion tissue and 79 cases of PTC tissue and peritumoral non-malignant tissue were detected by immunohistochemical staining. Expressions of SDF-1 and CXCR7 were negative in peritumoral non-malignant tissues. Respectively, positive expression rates of SDF-1 and CXCR7 were 69.6 and 65.8 % in PTC, 12.1 and 30.3 % in thyroid benign tissue. The expression of SDF-1 and CXCR7 were positively correlated with lymph node metastasis. SDF-1 and CXCR7 expressions were related with the lymph nodes metastasis of PTC.

Indexed as

AdultBiomarkers, TumorCarcinomaCarcinoma, PapillaryChemokine CXCL12Disease ProgressionFemaleHumansImmunohistochemistryLymph NodesMaleMiddle AgedReceptors, CXCRThyroid Cancer, PapillaryThyroid NeoplasmsACKR3 protein, humanBiomarkers, TumorChemokine CXCL12Receptors, CXCR

Identifiers

PMID23070788
OpenAlexW2072821087

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.