ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2013
Determinants of health-related quality of life in people with Parkinson's disease: a path analysis.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
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Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review for the prevention and management of falls and fear of falling in patients with Parkinson's disease.Brain and behavior · 2022Pooled it
- Efficacy of repetitive transcranial magnetic stimulation for improving lower limb function in individuals with neurological disorders: A systematic review and meta-analysis of randomized sham-controlled trials.Journal of rehabilitation medicine · 2022Pooled it
- The effects of exergames on upper extremity performance, trunk mobility, gait, balance, and cognition in Parkinson's disease: a randomized controlled study.Acta neurologica Belgica · 2024Trial
- Digital Intervention Promoting Physical Activity in People Newly Diagnosed with Parkinson's Disease: Feasibility and Acceptability of the Knowledge, Exercise-Efficacy and Participation (KEEP) Intervention.Journal of Parkinson's disease · 2024Trial
- Trial
- Interference of functional dual-tasks on gait in untrained people with Parkinson's disease and healthy controls: a cross-sectional study.BMC musculoskeletal disorders · 2020Trial
- Effects of whole-body vibration training on physical function, bone and muscle mass in adolescents and young adults with cerebral palsy.Scientific reports · 2016Trial
- Protocol for a randomized comparison of integrated versus consecutive dual task practice in Parkinson's disease: the DUALITY trial.BMC neurology · 2014Trial
- Article
- Walkbot-Based Robot-Assisted Gait Training and Phase-Specific Lower-Limb Torque in Parkinson's Disease: A Retrospective Comparative Study.Brain sciences · 2026Article
- Article
- Article
- Handwriting, touchscreen dexterity and bradykinesia measures in Parkinson's disease: a feature selection study.Journal of neurology · 2025Article
- Neural correlates of bradykinesia in Parkinson's disease: a kinematic and functional MRI study.NPJ Parkinson's disease · 2024Article
- Factors associated with self-rated health in people with late-stage parkinson's and cognitive impairment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Development and validation of fall risk perception scale for patients with Parkinson's disease.Frontiers in psychology · 2024Article
- Patient Empowerment for Those Living with Parkinson's Disease.Journal of Parkinson's disease · 2024Review
- Social deprivation and exclusion in Parkinson's disease: a cross-sectional and longitudinal study.BMJ open · 2023Article
- Depressive symptoms in Parkinson's disease are insufficiently but more often treated than in other chronic conditions.NPJ Parkinson's disease · 2023Article
- Occupational performance skills in Parkinson's disease: relationship with health-related quality of life and caregiver burden.Revista de neurologia · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo identify the demographic factors, impairments and activity limitations that contribute to health-related quality of life (HRQOL) in people with idiopathic Parkinson's disease (PD).
methodTwo hundred and ten individuals with idiopathic PD who participated in the baseline assessment of a randomized clinical trial were included. The Parkinson's Disease Questionnaire-39 summary index was used to quantify HRQOL. In order to provide greater clarity regarding the determinants of HRQOL, path analysis was used to explore the relationships between the various predictors in relation to the functioning and disability framework of the International Classification of Functioning model.
resultsThe two models of HRQOL that were examined in this study had a reasonable fit with the data. Activity limitations were found to be the strongest predictor of HRQOL. Limitations in performing self-care activities contributed the most to HRQOL in Model 1 (β = 0.38; p < 0.05), while limitations in functional mobility had the largest contribution in Model 2 (β = -0.31; p < 0.0005). Self-reported history of falls was also found to have a significant and direct relationship with HRQOL in both models (Model 1 β = -0.11; p < 0.05; Model 2 β = -0.21; p < 0.05).
conclusionsHealth-related quality of life in PD is associated with self-care limitations, mobility limitations, self-reported history of falls and disease duration. Understanding how these factors are inter-related may assist clinicians focus their assessments and develop strategies that aim to minimize the negative functional and social sequelae of this debilitating disease.
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